1,053
Participants
Start Date
May 31, 2005
Primary Completion Date
March 31, 2008
Study Completion Date
April 30, 2008
S-1/Cisplatin
"In Arm A, S-1 25 mg/m2 was taken orally two times daily for 21 days followed by a 7-day recovery period. The patient was instructed to have nothing by mouth (NPO 1 hour prior to and 1 hour after S-1 administration. S-1 was taken with approximately 8 ounces of water and prior to cisplatin infusion on Day 1.~Cisplatin 75 mg/m2 was administered as a 1- to 3-hour IV infusion after the morning dose of S-1 on Day 1 of each cycle. This regimen was repeated every 4 weeks with a maximum of 6 cycles of treatment for cisplatin."
5-FU/cisplatin
In Arm B, 5-FU 1000 mg/m2/24 hours was administered CIV on Days 1 through 5 following cisplatin 100 mg/m2 administered IV as a 1- to 3-hour infusion on Day 1. This regimen was repeated every 4 weeks with a maximum of 6 cycles of treatment for cisplatin.
Hoo Chun, MD, Hawthorne
Hematology/Oncology Associates of Rockland, New City
Abramson Cancer Center, Philadelphia
Thomas Jefferson University, Philadelphia
New Bern Cancer Care, New Bern
Charleston Cancer Center, Charleston
Broward Oncology Associates, Fort Lauderdale
Palm Beach Cancer Institute, West Palm Beach
Alexandar Rosemurgy, Tampa
Clearview Cancer Center, Huntsville
Associates in Oncology and Hematology, Chattanooga
Lexington Oncology Associates, Chattanooga
University of Wisconsin Comprehensive Cancer Center, Madison
St. Lukes Cancer Care Center, Duluth
Robert H. Lurie Comprehensive Cancer Center, Chicago
Neuroscience Center, St Louis
St. Louis University Cancer Center, St Louis
Oncology and Hematology, Metairie
MD Anderson Cancer Center, Houston
Western Hematology/Oncology, Lakewood
AHS Lovelace Medical Group,LLC, Albuquerque
New Mexico Cancer Center Associates, Albuquerque
University of New Mexico, Albuquerque
Southern Nevada Cancer Research Foundation, Las Vegas
Norris Cancer Center, Los Angeles
Premiere Oncology, Santa Monica
Saint Joseph Medical Center, Burbank
Comprehensive Cancer Center, Palm Springs
Saint Francis Memorial Hospital, San Francisco
Dr. Ronald Yanagihara, Gilroy
Straub Clinic and Hospital, Honolulu
University of Chicago Medical Center, Chicago
CHUM Hopital Saint-Luc, Montreal
Quintiles, Inc.
INDUSTRY
Taiho Oncology, Inc.
INDUSTRY