A Study of Hyaluronan for the Treatment of Osteoarthritis in the Thumb

PHASE3CompletedINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

August 31, 2006

Primary Completion Date

March 31, 2013

Study Completion Date

March 31, 2013

Conditions
Osteoarthritis
Interventions
DRUG

Synvisc (Hylan G-F20; hyaluronan injection)

1 ml of hyaluronan (Synvisc) injected once a week for 2 consecutive weeks

DRUG

Bupivicaine (local anesthesia injection)

1 ml of bupivicaine 0.5% injected once a week for 2 weeks

DRUG

Kenalog (triamcinolone; corticosteroid injection)

1 ml (40mg) of triamcinolone (Kenalog) injected the first week, followed by a placebo injection of 1 ml 0.5% bupivacaine the second week; Kenalog is a non-suspension steroid preparation and is less likely to cause post-injection flares than a suspension preparation

Trial Locations (1)

10021

Hospital for Special Surgery, New York

All Listed Sponsors
collaborator

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NIH

collaborator

Genzyme, a Sanofi Company

INDUSTRY

lead

Hospital for Special Surgery, New York

OTHER

NCT00398866 - A Study of Hyaluronan for the Treatment of Osteoarthritis in the Thumb | Biotech Hunter | Biotech Hunter