N-acetylcysteine in Intra-amniotic Infection/Inflammation

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

68

Participants

Timeline

Start Date

October 1, 2006

Primary Completion Date

October 29, 2012

Study Completion Date

August 1, 2018

Conditions
Labor, PrematurePreterm Premature Rupture of the MembranesInfectionInflammationChorioamnionitis
Interventions
PROCEDURE

amniocentesis

Amniotic fluid will be retrieved for routine amniocentesis to rule-out or confirm intra-amniotic infection and /or inflammation. The amniocentesis procedure will be clinically indicated and the patient will undergo the procedure independent of our study.

DRUG

N-acetylcysteine or placebo

Only women with amniocentesis results consistent with infection/inflammation will be randomized

Trial Locations (2)

43215

The Research Institute at Nationwide Children's Hospital, Columbus

06510

Yale New Haven Hospital, New Haven

All Listed Sponsors
lead

Ohio State University

OTHER

NCT00397735 - N-acetylcysteine in Intra-amniotic Infection/Inflammation | Biotech Hunter | Biotech Hunter