NCT00393445 - Exendin(9-39)Amide as a Glucagon-like Peptide-1 (GLP-1) Receptor Antagonist in Humans | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

November 30, 2006

Study Completion Date

May 31, 2007

Conditions

Hyperglycemia

Interventions

DRUG

GLP-1 control

intravenous infusion of GLP-1

DRUG

GLP-1 and Exendin(9-39) 300

intravenous infusion of exendin(9-39) at 300 pmol/kg/min during GLP-1 at 0.3 and 0.9 pmol/kg/min

DRUG

saline control

intravenous infusion of saline

DRUG

GLP-1 and Exendin(9-39) 600

intravenous infusion of exendin(9-39) at 600 pmol/kg/min during GLP-1 at 0.3 and 0.9 pmol/kg/min

DRUG

GLP-1 and Exendin(9-39) 900

intravenous infusion of exendin(9-39) at 900 pmol/kg/min during GLP-1 at 0.3 and 0.9 pmol/kg/min

DRUG

GLP-1 and Exendin(9-39) 1200

intravenous infusion of exendin(9-39) at 1200 pmol/kg/min during GLP-1 at 0.3 and 0.9 pmol/kg/min

Trial Locations (1)

Ludwig Maximilians University, Clinical Research Unit, Munich