Rituximab and Combination Chemotherapy in Treating Patients With Newly Diagnosed, HIV-Associated Burkitt's Lymphoma

PHASE2CompletedINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

September 30, 2006

Primary Completion Date

July 31, 2011

Study Completion Date

July 31, 2013

Conditions
Lymphoma
Interventions
BIOLOGICAL

filgrastim

given subcutaneously

BIOLOGICAL

pegfilgrastim

given subcutaneously

BIOLOGICAL

rituximab

given IV

DRUG

cyclophosphamide

given IV

DRUG

cytarabine

given intrathecally

DRUG

doxorubicin hydrochloride

given IV

DRUG

etoposide

given IV

DRUG

ifosfamide

given IV

DRUG

leucovorin calcium

given IV

DRUG

liposomal cytarabine

given intrathecally

DRUG

methotrexate

given intrathecally

DRUG

therapeutic hydrocortisone

given intrathecally

DRUG

vincristine sulfate

given IV

Trial Locations (13)

10065

Memorial Sloan-Kettering Cancer Center, New York

10461

Albert Einstein Cancer Center at Albert Einstein College of Medicine, The Bronx

19106

Pennsylvania Oncology Hematology Associates, Incorporated - Philadelphia, Philadelphia

25304

West Virginia University Health Sciences Center - Charleston, Charleston

63110

Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis, St Louis

98101

Floyd and Delores Jones Cancer Institute at Virginia Mason Medical Center, Seattle

92093-0658

Rebecca and John Moores UCSD Cancer Center, La Jolla

90089-9181

USC/Norris Comprehensive Cancer Center and Hospital, Los Angeles

90095-1793

UCLA Clinical AIDS Research and Education (CARE) Center, Los Angeles

94143-0296

UCSF Medical Center at Parnassus, San Francisco

21231-2410

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore

02215

Beth Israel Deaconess Medical Center, Boston

43210-1240

Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center, Columbus

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

collaborator

The Emmes Company, LLC

INDUSTRY

lead

AIDS Malignancy Consortium

NETWORK

NCT00392834 - Rituximab and Combination Chemotherapy in Treating Patients With Newly Diagnosed, HIV-Associated Burkitt's Lymphoma | Biotech Hunter | Biotech Hunter