616
Participants
Start Date
February 28, 2007
Primary Completion Date
February 28, 2010
Study Completion Date
July 31, 2010
Bosentan
Bosentan 62.5 mg tablets twice daily (b.i.d.) for 4 weeks followed by bosentan 125 mg tablets b.i.d (if body weight \> 40 kg) or bosentan 62.5 mg tablets b.i.d. (if body weight \< 40 kg)
Placebo
Placebo matching bosentan 62.5 mg tablets and 125 mg tablets
Lead Sponsor
Actelion
INDUSTRY