An Oral p38 Inhibitor Investigating Safety, Efficacy, And PK In Subjects With Active Rheumatoid Arthritis

PHASE2CompletedINTERVENTIONAL
Enrollment

305

Participants

Timeline

Start Date

December 15, 2006

Primary Completion Date

July 1, 2008

Study Completion Date

July 16, 2008

Conditions
Arthritis, Rheumatoid
Interventions
DRUG

placebo

Capsule, once daily (QD) for 12 weeks

DRUG

PH-797804

Capsule, 0.5 mg of PH-797804, once daily (QD) for 12 weeks

DRUG

PH-797804

Capsule, 3 mg of PH-797804, once daily (QD) for 12 weeks

DRUG

PH-797804

Capsule, 6 mg of PH-797804, once daily (QD) for 12 weeks

DRUG

PH-797804

Capsule, 10 mg of PH-797804, once daily (QD) for 12 weeks

Trial Locations (48)

1619

Office Of Dr. F. Le Clus, Johannesburg

2193

Dr S Sankovic, Parktown

3145

Emeritus Research, Malvern East

4001

St Augustines Medical Ctr 2, Durban

9317

Quinta-Med, Bloemfontein

11312

East Tallinn Central Hospital, Tallinn

13419

North Estonia Regional Hospital, Tallinn

41014

Hospital Nuestra Señora de Valme, Seville

48903

Hospital de Cruces, Barakaldo

115093

City Hospital #4, Department of Therapy of Moscow Faculty of Russian State Medical University, Moscow

115446

Clinical Hospital #7, Moscow

141001

Dayanand Medical College and Hospital, Department of Orthopedics, Ludhiana

190000

"City Hospital # 28 Maximilianovskaya", Saint Petersburg

194291

St. Petersburg Clnical Hospital n.a. Sokolov (MSCh #122), Saint Petersburg

214019

Smolensk State Medical Academy, Smolensk

2570017

Hospital Gustavo Fricke, Viña del Mar

7500922

Hospital del Salvador, Santiago

8331030

Office of Dr. Pedro Miranda, Santiago

8360156

Hospital Clínica San Borja Arriarán, Santiago

80060-240

Centro de Estudos em Terapias Inovadoras, Curitiba

80060-900

Hospital de Clínicas da UFPR, Curitiba

04026-000

Escola Paulista de Medicina - EPM, São Paulo

04230-000

Hospital Heliópolis - PAM, São Paulo

Unknown

Hospital Regional de Rancagua, Rancagua

Clinresco Centres (Pty) Ltd, Kempton Park

The Catholic University of Korea, Kangnam St. Mary's Hospital/ Rheumatology, Internal Medicine, Seoul

656 91

Fakultni nemocnice u sv. Anny v Brne, Brno

775 20

Fakultni nemocnice Olomouc, Olomouc

722 00

NZZ Bormed, s.r.o., Ostrava - Trebovice

128 50

Revmatologicky ustav, Prague

140 59

Fakultni Thomayerova nemocnice s poliklinikou, Prague

760 01

PV-Medical s.r.o., Zlín

500 034

Department of Rheumatology, CARE Hospital, Hyderabad

500 082

Nizam's Institute of Medical Sciences, Department of Rheumatology, Hyderabad

560 034

St. John's Medical College Hospital, Department of Orthopedics, Bangalore

400 008

T. N. Medical College and B. Y. L. Nair Ch. HospitalDepartment of Medicine and Rheumatology Clinic, Mumbai

641 014

Kovai Medical Center and Hospital,, Coimbatore

L-27

Instituto Peruano del Hueso y la Articulación SAC., Lima

L27

Instituto Peruano del Climaterio, Lima

L33

Instituto de Ginecologia y Reproduccion, Lima

15-950

SP ZOZ Wojewodzki Szpital Zespolony im. Jedrzeja Sniadeckiego, Bialystok

16-461

Centrum Osteoporozy i Chorob Kostno-Stawowych, Bialystok

60-773

Poznanski Osrodek Medyczny, Poznan

02-256

Centrum Badan Klinicznych, Warsaw

0081

Intercare Medical and Dental Centre, Pretoria

431-070

Hallym University Sacred Heart Hospital/Rheumatology, Internal Medicine, Anyang

120-752

Yonsei University College of Medicine, Severance Hospital, Rheumatology, Internal Medicine, Seoul

133-792

Hanyang University Hospital, Department of Rheumatology, Seoul

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY