NCT00379574 - Bortezomib Plus CHOP Every 2 Weeks for Advanced Stage DLBCL | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

September 30, 2006

Primary Completion Date

January 31, 2011

Study Completion Date

January 31, 2011

Conditions

Lymphoma, Large-Cell, DiffuseLymphoma, B-Cell

Interventions

DRUG

Bortezomib

"Bortezomib:~For phase I, 3 dose levels (1.0, 1.3 or 1.6 mg/m2), days 1 and 4, every 2 weeks.~For phase II, suggested dose of Bortezomib through phase I, days 1 and 4, every 2 weeks."

DRUG

Cyclophosphamide

cyclophosphamide 750mg/m2 day 1, every 2 weeks

DRUG

Doxorubicin

doxorubicin 50 mg/m2 day 1, every 2 weeks

DRUG

Vincristine

vincristine 1.4 mg/m2 (max. 2 mg) day 1, every 2 weeks

DRUG

Prednisolone

prednisolone 100 mg days 1-5, every 2 weeks

DRUG

Lenograstim

Lenograstim 5 microgram/kg subcutaneously days 4-13 every 2 weeks

Trial Locations (2)

138-736

Asan Medical Center, University of Ulsan College of Medicine, Seoul

Unknown

Asan Medical Cener, Seoul