Treatment of Acute Sinusitis

PHASE4CompletedINTERVENTIONAL
Enrollment

172

Participants

Timeline

Start Date

October 31, 2006

Primary Completion Date

May 31, 2009

Study Completion Date

August 31, 2010

Conditions
Acute Respiratory InfectionsAcute Rhinosinusitis
Interventions
DRUG

Acetaminophen

"Symptomatic treatment:~Dose: 500mg every 4 to 6 hours for pain or fever"

DRUG

Amoxicillin

"Intervention drug:~Dose: 500mg tid for 10 days"

DRUG

Dextromethorphan hydrobromide with guaifenesin

"Symptomatic treatment:~Dose: 10mls every 4 to 6 hours for cough"

DRUG

Guaifenesin

"Symptomatic treatment:~Dose: 600mg every 12 hours to thin secretions"

DRUG

Pseudoephedrine Sustained Action

"Symptomatic treatment:~Dose: 120mg every 12 hours for nasal congestion"

DRUG

Saline spray (0.65%)

"Symptomatic treatment:~Dose: 2 squeezes per nostril as needed for nasal congestion"

Trial Locations (1)

63110

Washington University in St. Louis, St Louis

All Listed Sponsors
collaborator

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

lead

Washington University School of Medicine

OTHER

NCT00377403 - Treatment of Acute Sinusitis | Biotech Hunter | Biotech Hunter