NCT00369590View on ClinicalTrials.gov

VEGF Trap in Treating Patients With Recurrent Malignant Gliomas That Did Not Respond to Temozolomide

PHASE2CompletedINTERVENTIONAL
Enrollment

58

Participants

Timeline

Start Date

August 31, 2006

Primary Completion Date

December 31, 2011

Study Completion Date

October 31, 2012

Conditions
Adult Anaplastic AstrocytomaAdult Anaplastic OligodendrogliomaAdult Giant Cell GlioblastomaAdult GliosarcomaRecurrent Adult Brain Tumor
Interventions
BIOLOGICAL

ziv-aflibercept

Given IV

OTHER

pharmacological study

correlative studies

OTHER

laboratory biomarker analysis

correlative studies

Trial Locations (7)

10065

Memorial Sloan-Kettering Cancer Center, New York

15232

University of Pittsburgh, Pittsburgh

53792

University of Wisconsin Hospital and Clinics, Madison

77030

M D Anderson Cancer Center, Houston

90095

University of California Los Angeles, Los Angeles

94115

University of California San Francisco, San Francisco

02115

Dana-Farber Cancer Institute, Boston

All Listed Sponsors
lead

National Cancer Institute (NCI)

NIH

NCT00369590 - VEGF Trap in Treating Patients With Recurrent Malignant Gliomas That Did Not Respond to Temozolomide | Biotech Hunter | Biotech Hunter