A Drug Interaction Study Between Tocilizumab, Methotrexate and Simvastatin on Patients With Rheumatoid Arthritis.

PHASE1CompletedINTERVENTIONAL
Enrollment

23

Participants

Timeline

Start Date

Not specified

Study Completion Date

April 30, 2008

Conditions
Rheumatoid Arthritis
Interventions
DRUG

tocilizumab [RoActemra/Actemra]

10mg/kg iv on day 8

DRUG

Methotrexate

10-25mg po/week

DRUG

Simvastatin

40mg po on days 1, 15 and 43

Trial Locations (11)

16635

Duncansville

32216

Jacksonville

34684

Palm Harbor

36207

Anniston

48073

Royal Oak

68154

Omaha

72202

Little Rock

73103

Oklahoma City

78704

Austin

85251

Scottsdale

Unknown

Christchurch

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY

NCT00365001 - A Drug Interaction Study Between Tocilizumab, Methotrexate and Simvastatin on Patients With Rheumatoid Arthritis. | Biotech Hunter | Biotech Hunter