Exubera Large Simple Trial To Evaluate Long-Term Pulmonary And Cardiovascular Safety

PHASE4CompletedINTERVENTIONAL
Enrollment

1,976

Participants

Timeline

Start Date

July 31, 2006

Primary Completion Date

December 31, 2008

Study Completion Date

April 30, 2009

Conditions
Diabetes Mellitus
Interventions
DRUG

Randomization to Exubera (insulin human [rDNA origin] inhalation powder) or Usual Diabetes Care

Subjects are randomized to use Exubera. Following initial use of randomized treatment, physicians and subjects are free to change regimens and dosing based on subject response to assigned treatment (as consistent with routine practice). Enrolling physicians are provided with the approved local label for Exubera to guide prescribing and treatment decisions.

DRUG

Randomization to Exubera (insulin human [rDNA origin] inhalation powder) or Usual Diabetes Care

Subjects are randomized to use usual diabetes care. Following initial use of randomized treatment, physicians and subjects are free to change regimens and dosing based on subject response to assigned treatment (as consistent with routine practice).

Trial Locations (197)

11224

Pfizer Investigational Site, Brooklyn

11702

Pfizer Investigational Site, Babylon

12247

Pfizer Investigational Site, Berlin

13355

Pfizer Investigational Site, Berlin

13413

Pfizer Investigational Site, New Hartford

14221

Pfizer Investigational Site, Williamsville

14612

Pfizer Investigational Site, Falkensee

14622

Pfizer Investigational Site, Rochester

15644

Pfizer Investigational Site, Jeannette

16684

Pfizer Investigational Site, Tipton

17018

Pfizer Investigational Site, Dauphin

17112

Pfizer Investigational Site, Harrisburg

17331

Pfizer Investigational Site, Hanover

17740

Pfizer Investigational Site, Jersey Shore

18051

Pfizer Investigational Site, Fogelsville

18209

Pfizer Investigational Site, Bad Doberan

19008

Pfizer Investigational Site, Broomall

19046

Pfizer Investigational Site, Jenkintown

19401

Pfizer Investigational Site, Norristown

19462

Pfizer Investigational Site, Plymouth Meeting

19806

Pfizer Investigational Site, Wilmington

20902

Pfizer Investigational Site, Wheaton

21061

Pfizer Investigational Site, Glen Burnie

21073

Pfizer Investigational Site, Hamburg

21204

Pfizer Investigational Site, Baltimore

21921

Pfizer Investigational Site, Elkton

22041

Pfizer Investigational Site, Hamburg

23320

Pfizer Investigational Site, Chesapeake

23803

Pfizer Investigational Site, Ettrick

23858

Pfizer Investigational Site, Reinfeld

25314

Pfizer Investigational Site, Charleston

26335

Pfizer Investigational Site, Burnsville

26725

Pfizer Investigational Site, Emden

27103

Pfizer Investigational Site, Winston-Salem

27203

Pfizer Investigational Site, Asheboro

27609

Pfizer Investigational Site, Raleigh

27610

Pfizer Investigational Site, Raleigh

28150

Pfizer Investigational Site, Shelby

28227

Pfizer Investigational Site, Charlotte

28463

Pfizer Investigational Site, Tabor City

29412

Pfizer Investigational Site, Charleston

29501

Pfizer Investigational Site, Florence

29582

Pfizer Investigational Site, North Myrtle Beach

29651

Pfizer Investigational Site, Greer

30013

Pfizer Investigational Site, Conyers

30035

Pfizer Investigational Site, Decatur

30342

Pfizer Investigational Site, Atlanta

31088

Pfizer Investigational Site, Warner Robins

32043

Pfizer Investigational Site, Green Cove Springs

32174

Pfizer Investigational Site, Ormond Beach

32446

Pfizer Investigational Site, Marianna

32549

Pfizer Investigational Site, Bad Oeynhausen

32578

Pfizer Investigational Site, Niceville

32605

Pfizer Investigational Site, Gainesville

32713

Pfizer Investigational Site, DeBary

32763

Pfizer Investigational Site, Orange City

32952

Pfizer Investigational Site, Merritt Island

33021

Pfizer Investigational Site, Hollywood

33027

Pfizer Investigational Site, Pembroke Pines

33144

Pfizer Investigational Site, Miami

33324

Pfizer Investigational Site, Plantation

33433

Pfizer Investigational Site, Boca Raton

33607

Pfizer Investigational Site, Tampa

33624

Pfizer Investigational Site, Tampa

33756

Pfizer Investigational Site, Clearwater

33952

Pfizer Investigational Site, Port Charlotte

34414

Pfizer Investigational Site, Warburg

34741

Pfizer Investigational Site, Kissimmee

34743

Pfizer Investigational Site, Kissimmee

35073

Pfizer Investigational Site, Graysville

35125

Pfizer Investigational Site, Pell City

36037

Pfizer Investigational Site, Fulda

36381

Pfizer Investigational Site, Schlüchtern

36532

Pfizer Investigational Site, Fairhope

38138

Pfizer Investigational Site, Germantown

40258

Pfizer Investigational Site, Louisville

40353

Pfizer Investigational Site, Mount Sterling

41345

Pfizer Investigational Site, Gothenburg

43207

Pfizer Investigational Site, Columbus

43701

Pfizer Investigational Site, Zanesville

43756

Pfizer Investigational Site, McConnelsville

44004

Pfizer Investigational Site, Ashtabula

44113

Pfizer Investigational Site, Cleveland

44137

Pfizer Investigational Site, Dortmund

44339

Pfizer Investigational Site, Dortmund

44708

Pfizer Investigational Site, Canton

45329

Pfizer Investigational Site, Essen

45419

Pfizer Investigational Site, Dayton

45711

Pfizer Investigational Site, Datteln

45770

Pfizer Investigational Site, Marl

46038

Pfizer Investigational Site, Fishers

46229

Pfizer Investigational Site, Indianapolis

46330

Pfizer Investigational Site, Lilla Edet

48084

Pfizer Investigational Site, Troy

48091

Pfizer Investigational Site, Warren

48104

Pfizer Investigational Site, Ann Arbor

48145

Pfizer Investigational Site, Münster

48153

Pfizer Investigational Site, Münster

48310

Pfizer Investigational Site, Sterling Heights

48504

Pfizer Investigational Site, Flint

49014

Pfizer Investigational Site, Battle Creek

49017

Pfizer Investigational Site, Battle Creek

49236

Pfizer Investigational Site, Clinton

49444

Pfizer Investigational Site, Muskegon

50315

Pfizer Investigational Site, Des Moines

51069

Pfizer Investigational Site, Cologne

51371

Pfizer Investigational Site, Leverkusen

53179

Pfizer Investigational Site, Bonn

56301

Pfizer Investigational Site, Saint Cloud

56564

Pfizer Investigational Site, Neuwied

57072

Pfizer Investigational Site, Siegen

58091

Pfizer Investigational Site, Hagen

58501

Pfizer Investigational Site, Bismarck

60048

Pfizer Investigational Site, Libertyville

62246

Pfizer Investigational Site, Greenville

63739

Pfizer Investigational Site, Aschaffenburg

68161

Pfizer Investigational Site, Mannheim

68803

Pfizer Investigational Site, Grand Island

71111

Pfizer Investigational Site, Bossier City

72143

Pfizer Investigational Site, Searcy

72335

Pfizer Investigational Site, Forrest City

73601

Pfizer Investigational Site, Clinton

73728

Pfizer Investigational Site, Esslingen am Neckar

75041

Pfizer Investigational Site, Garland

75142

Pfizer Investigational Site, Kaufman

76054

Pfizer Investigational Site, Hurst

76401

Pfizer Investigational Site, Stephenville

77598

Pfizer Investigational Site, Webster

77972

Pfizer Investigational Site, Mahlberg

78054

Pfizer Investigational Site, Villingen-Schwenningen

78229

Pfizer Investigational Site, San Antonio

78414

Pfizer Investigational Site, Corpus Christi

78666

Pfizer Investigational Site, San Marcos

79410

Pfizer Investigational Site, Lubbock

79705

Pfizer Investigational Site, Midland

80219

Pfizer Investigational Site, Denver

83704

Pfizer Investigational Site, Boise

84041

Pfizer Investigational Site, Layton

85016

Pfizer Investigational Site, Phoenix

85028

Pfizer Investigational Site, Phoenix

85029

Pfizer Investigational Site, Phoenix

86316

Pfizer Investigational Site, Friedberg

87106

Pfizer Investigational Site, Albuquerque

87730

Pfizer Investigational Site, Bad Grönenbach

88239

Pfizer Investigational Site, Wangen

Pfizer Investigational Site, Wangen I. Allgaeu

88677

Pfizer Investigational Site, Markdorf

89452

Pfizer Investigational Site, Incline Village

90201

Pfizer Investigational Site, Cudahy

90274

Pfizer Investigational Site, Rolling Hills Estates

90480

Pfizer Investigational Site, Nuremberg

92019

Pfizer Investigational Site, El Cajon

92648

Pfizer Investigational Site, Huntington Beach

92683

Pfizer Investigational Site, Westminster

92704

Pfizer Investigational Site, Santa Ana

95116

Pfizer Investigational Site, San Jose

96231

Pfizer Investigational Site, Bad Staffelstein

97701

Pfizer Investigational Site, Bend

98529

Pfizer Investigational Site, Suhl

99817

Pfizer Investigational Site, Eisenach

36507-4185

Pfizer Investigational Site, Bay Minette

06460

Pfizer Investigational Site, Milford

33054-3818

Pfizer Investigational Site, Opa-locka

30318-2513

Pfizer Investigational Site, Atlanta

46254-5472

Pfizer Investigational Site, Indianapolis

04210

Pfizer Investigational Site, Auburn

02110

Pfizer Investigational Site, Boston

02360

Pfizer Investigational Site, Plymouth

07109

Pfizer Investigational Site, Belleville

07823

Pfizer Investigational Site, Belvidere

08029

Pfizer Investigational Site, Glendora

28557-3126

Pfizer Investigational Site, Morehead City

19153-2326

Pfizer Investigational Site, Philadelphia

09130

Pfizer Investigational Site, Chemnitz

06679

Pfizer Investigational Site, Hohenmölsen

07743

Pfizer Investigational Site, Jena

01662

Pfizer Investigational Site, Meissen

01587

Pfizer Investigational Site, Riesa

00674

Pfizer Investigational Site, Manatí

503 30

Pfizer Investigational Site, Borås

667 32

Pfizer Investigational Site, Forshaga

S40 4TF

Pfizer Investigational Site, Chesterfield

TW15 3EA

Pfizer Investigational Site, Ashford

S18 1RU

Pfizer Investigational Site, Dronfield

KT15 2BH

Pfizer Investigational Site, Weybridge

GU22 7EY

Pfizer Investigational Site, Woking

CV22 5PX

Pfizer Investigational Site, Rugby

BA12 9AA

Pfizer Investigational Site, Warminster

S7 2DW

Pfizer Investigational Site, Sheffield

ML6 0JS

Pfizer Investigational Site, Airdrie

BA2 3HT

Pfizer Investigational Site, Bath

BA2 4BY

Pfizer Investigational Site, Bath

B37 7TR

Pfizer Investigational Site, Birmingham

LE1 5WW

Pfizer Investigational Site, Leicester

NE15 6TQ

Pfizer Investigational Site, Newcastle upon Tyne

NE3 3QJ

Pfizer Investigational Site, Newcastle upon Tyne

BA13 3JD

Pfizer Investigational Site, Westbury

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY