NCT00359658View on ClinicalTrials.gov

Withdrawal of Steroids, Cyclosporine A Dose Reduction and Switch to Mycophenolatmofetile After Heart Transplantation

NACompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

November 30, 2004

Primary Completion Date

June 30, 2008

Study Completion Date

June 30, 2008

Conditions
Heart Transplantation
Interventions
DRUG

prednisolon

prednisolon withdrawal: reduction of maintenance dosage, 0,5 mg of the daily dose every week till withdrawal

DRUG

Mycophenolatmofetile

Mycophenolatmofetile administration: start doses 250 mg, increase of the daily dose about 250 mg every week till reaching 2 g/daily

DRUG

Cyclosporin A

Cyclosporin A reduction: 8 weeks after starting prednisolon withdrawal and Mycophenolatmofetile administration reduction of Cyclosporin A trough level till a range from 50 to 90 ng/ml

Trial Locations (1)

30625

Hannover Medical School, Department of Thoracic and Cardiovascular Surgery, Hanover

All Listed Sponsors
collaborator

Hoffmann-La Roche

INDUSTRY

lead

Hannover Medical School

OTHER

NCT00359658 - Withdrawal of Steroids, Cyclosporine A Dose Reduction and Switch to Mycophenolatmofetile After Heart Transplantation | Biotech Hunter | Biotech Hunter