D-cycloserine and Virtual Reality Exposure to Treat Iraq War Veterans With PTSD

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

156

Participants

Timeline

Start Date

September 30, 2006

Primary Completion Date

June 30, 2014

Study Completion Date

June 30, 2014

Conditions
Stress Disorder, Post Traumatic
Interventions
DRUG

D-Cycloserine

D-Cycloserine doses will be 50 mg. There will be 5 pills total during study, each given 30 minutes prior to each VRE session.

DRUG

Alprazolam

Alprazolam doses will be 0.25 mg. There will be 5 pills total during study, each given 30 minutes prior to each VRE session.

BEHAVIORAL

Virtual Reality Exposure Therapy

VRE includes viewing scenes of virtual Iraq via a head mounted display. Other stimuli presented include sounds, smells and vibration. Each session will be 60 minutes with approximately 30 to 45 minutes of that wearing head mounted display.

DRUG

Placebo

Placebo will be administered in the same manner as the active drugs.

Trial Locations (1)

30329

Emory University, Atlanta

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

Emory University

OTHER

NCT00356278 - D-cycloserine and Virtual Reality Exposure to Treat Iraq War Veterans With PTSD | Biotech Hunter | Biotech Hunter