208
Participants
Start Date
July 31, 2006
Primary Completion Date
September 30, 2012
Study Completion Date
September 30, 2012
Talaporfin sodium
LS11 (Talaporfin Sodium) slowly administered (3-5 min.) in a free flowing intravenous drip at a dose of 1 mg/kg.
Interstitial Light Emitting Diodes
200 J/cm per Light Source at 20 mW/cm light energy
Percutaneous placement of device in the liver
Litx™ treatment group undergo CT or Ultrasound guided percutaneous placement of a single, two, three, or four Light Sources depending on their tumor characteristics. No more than 4 Light Sources will be used at a single treatment. The Light Source(s) may be used in a single lesion or in multiple lesions.
Standard Care
The standard of care could include any one of the following treatment options: Percutaneous Ethanol Injection (PEI), Transcatheter Arterial Chemoembolization (TACE), Radio Frequency Ablation (RFA), Cryotherapy, Systemic Chemotherapy, or other modalities that may be used at a particular institution.
Singapore General Hospital, Singapore
National Cancer Centre, Singapore
Cancer Clinic, Nagpur
University Hospital Dubrava, Zagreb
Tuen Mun Hospital, Tuenmen
Prince of Wales Hospital, Dept. of Clincal Oncology, New Territories
Dr. Kamakshi Memorial Hospital, Chennai
SMS Medical College, Jaipur
Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow
Shatabdi Super Specialty Hospital, Nashik
Island Hospital, George Town
Lam Wah Ee Hospital, George Town
Hospital Universiti Kebangsaan Malaysia, Kuala Lumpur
University Malaya Medical Centre, Kuala Lumpur
Cebu Doctors University Hospital, Cebu City
Vicente Sotto Memorial Medical Center, Cebu City
Santo Tomas University Hospital, Manila
The Medical City, Pasig
National Kidney and Transplant Institute, Quezon City
St. Luke's Medical Center, Quezon City
Szpital Uniwersytecki CMUJ, Krakow
Centralny Szpital Kliniczny MSWiA, Warsaw
Clinical Center of Serbia, Institute for Gastroenterology and Hepatology, Belgrade
Clinical Center of Serbia, Belgrade
Military Medical Academy, Belgrade
Pusan National University Hospital, Busan
Seoul National University Bundang Hospital, Gyeonggi-do
Korea University Medical Center Anam Hospital, Seoul
Kyunghee Univeristy Medical Center, Seoul
Samsung Medical Center, Seoul
Sinchon Severance Hospital, Yonsei University, Seoul
Karolinska University Hospital, Stockholm
Mahidol University, Siriraj Hospital, Bangkok
Chiang Mai University, Chiang Mai
Lead Sponsor
Light Sciences Oncology
INDUSTRY