Imatinib in Combination With Dacarbazine and Capecitabine in Medullary Thyroid Carcinoma

PHASE1/PHASE2TerminatedINTERVENTIONAL
Enrollment

21

Participants

Timeline

Start Date

December 31, 2004

Primary Completion Date

November 30, 2006

Study Completion Date

August 31, 2013

Conditions
Solid TumorThyroid Cancer
Interventions
DRUG

Capecitabine (Xeloda)

Starting Dose 500 mg/m\^2 twice a day Days 1-14 of 21 Day Cycle.

DRUG

DTIC-Dome (Dacarbazine)

Starting Dose 250 mg/m\^2 a day on Days 1-3 of 21 Day Cycle.

DRUG

Gleevec (Imatinib Mesylate)

Starting Dose 400 mg a day on Days 1-21 of 21 Day Cycle.

Trial Locations (1)

77030

UT MD Anderson Cancer Center, Houston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Novartis Pharmaceuticals

INDUSTRY

lead

M.D. Anderson Cancer Center

OTHER