81
Participants
Start Date
July 20, 2006
Primary Completion Date
May 31, 2015
Study Completion Date
November 15, 2022
Adriamycin®
Given IV on Day 1 of weeks 1, 3, 5, 7, 9 and 11.
Vinblastine
Given IV, Day 1 of weeks 1, 3, 5, 7, 9 and 11.
Nitrogen Mustard
Given IV, Day 1 of weeks 1, 5 and 9. Cyclophosphamide may be substituted if nitrogen mustard is unavailable.
Cyclophosphamide
May be substituted if nitrogen mustard is unavailable. Given on Day 1 of weeks 1, 5 and 9.
Vincristine
Given IV on Day 1 of weeks 2, 4, 6, 8, 10 and 12.
Bleomycin
Given IV on Day 1 of weeks 2, 4, 6, 8, 10 and 12.
Etoposide
Given IV on Days 1 and 2 of weeks 1-10.
Prednisone
Given PO every other day of weeks 1-12.
G-CSF
Given subcutaneously days 3-13, 16-26, 29-39, 42-52, 55-65, and 68-78 (as clinically indicated).
Radiotherapy
Participants receive radiotherapy after completion of 12 weeks of Stanford V chemotherapy.
St. Jude Children's Research Hospital, Memphis
Rady Children's Hospital San Diego, San Diego
Stanford University Medical Center, Palo Alto
Maine Children's Medical Center, Portland
Massachusetts General Hospital, Boston
Dana-Farber Cancer Institute, Boston
St. Jude Children's Research Hospital
OTHER