Switch Study of Existing Atypical Antipsychotics to Bifeprunox

PHASE3CompletedINTERVENTIONAL
Enrollment

286

Participants

Timeline

Start Date

December 31, 2006

Primary Completion Date

February 29, 2008

Study Completion Date

February 29, 2008

Conditions
Schizophrenia and Schizoaffective Disorder
Interventions
DRUG

Aripiprazole

Abrupt discontinuation of prior anti-psychotic med after a successful eight-day up titration of bifeprunox

DRUG

Olanzapine

Abrupt discontinuation of prior anti-psychotic med after a successful eight-day up titration of bifeprunox

DRUG

Risperidone

Abrupt discontinuation of prior anti-psychotic med after a successful eight-day up titration of bifeprunox

DRUG

Quetiapine

Abrupt discontinuation of prior anti-psychotic med after a successful eight-day up titration of bifeprunox

DRUG

Ziprasidone

Abrupt discontinuation of prior anti-psychotic med after a successful eight-day up titration of bifeprunox

DRUG

Aripiprazole

Cross-tapering during which prior anti-psychotic med will be tapered off at the same time while bifeprunox is being titrated up within 8 days

DRUG

Olanzapine

Cross-tapering during which prior anti-psychotic med will be tapered off at the same time while bifeprunox is being titrated up within 8 days

DRUG

Risperidone

Cross-tapering during which prior anti-psychotic med will be tapered off at the same time while bifeprunox is being titrated up within 8 days

DRUG

Quetiapine

Cross-tapering during which prior anti-psychotic med will be tapered off at the same time while bifeprunox is being titrated up within 8 days

DRUG

Ziprasidone

Cross-tapering during which prior anti-psychotic med will be tapered off at the same time while bifeprunox is being titrated up within 8 days

Trial Locations (122)

Unknown

Site 148, Birmingham

Site 194, Little Rock

Site 178, Anaheim

Site 167, Cerritos

Site 189, Cerritos

Site 183, Culver City

Site 140, Garden Grove

Site 162, La Palma

Site 190, Long Beach

Site 173, Oceanside

Site 175, Paramount

Site 136, Pasadena

Site 184, Sacramento

Site 152, San Diego

Site 186, San Diego

Site 133, Santa Ana

Site 171, Torrance

Site 197, Boca Raton

Site 156, Gainesville

Site 188, Hialeah

Site 193, Jacksonville

Site 154, Miami

Site 163, North Miami

Site 168, North Miami

Site 166, Orange City

Site 124, Orlando

Site 187, Tampa

Site 161, Atlanta

Site 128, Augusta

Site 122, Decatur

Site 174, Chicago

Site 164, Indianapolis

Site 172, Lake Charles

Site 182, Shreveport

Site 121, Glen Burnie

Site 159, Detroit

Site 153, Minneapolis

Site 145, Saint Charles

Site 130, St Louis

Site 141, St Louis

Site 142, Clementon

Site 180, Kenilworth

Site 129, Albuquerque

Site 131, Brooklyn

Site 181, Cedarhurst

Site 169, Jamaica

Site 195, New York

Site 147, Staten Island

Site 127, Chagrin Falls

Site 176, Cincinnati

Site 191, Oklahoma City

Site 146, Philadelphia

Site 179, Philadelphia

Site 196, Sioux Falls

Site 134, Memphis

Site 170, Memphis

Site 177, Austin

Site 185, Conroe

Site 126, Houston

Site 151, San Antonio

Site 138, Richmond

Site 198, Spokane

Site 165, Huntington

Site 302, Buenos Aires

Site 305, Buenos Aires

Site 306, Córdoba

Site 307, La Plata

Site 301, Mendoza

Site 304, Mendoza

Site 308, Mendoza

Site 303, Rosario

Site 116, Chatham

Site 117, Mississauga

Site 100, Calgary

Site 101, Claresholm

Site 110, Halifax

Site 111, Hull

Site 107, Kelowna

Site 109, Kingston

Site 115, Markham

Site 112, Medicine Hat

Site 108, Orléans

Site 106, Ottawa

Site 104, Prince Albert

Site 102, Sherbrooke

Site 114, Victoria

Site 113, Winnipeg

Site 235, Bolonska

Site 234, Jablonova

Site 216, Litoměřice

Site 233, Na Markvartce

Site 213, Olomouc

Site 214, Pilsen

Site 215, Prague

Site 217, Prague

Site 236, Rejskovo Namesti

Site 231, Paldksi Mnt

Site 229, Tartu

Site 230, Võru

Site 202, Clermont-Ferrand

Site 203, Dole

Site 201, Saint-Cyr-au-Mont-d'Or

Site 206, Balassagyarmat

Site 204, Budapest

Site 205, Budapest

Site 208, Budapest

Site 211, Budapest

Site 207, Debrecen

Site 212, Győr

Site 209, Gyula

Site 210, Pécs

Site 219, Balvi

Site 221, Jelgava

Site 218, Liepāja

Site 222, Riga

Site 220, Sigulda

Site 225, Kaunas

Site 226, Kaunas

Site 223, Klaipėda

Site 232, Šilutė

Site 224, Vilnius

Site 228, Vilnius

All Listed Sponsors
collaborator

H. Lundbeck A/S

INDUSTRY

collaborator

Wyeth is now a wholly owned subsidiary of Pfizer

INDUSTRY

lead

Solvay Pharmaceuticals

INDUSTRY

NCT00347425 - Switch Study of Existing Atypical Antipsychotics to Bifeprunox | Biotech Hunter | Biotech Hunter