70
Participants
Start Date
April 10, 2006
Primary Completion Date
July 1, 2013
Study Completion Date
July 31, 2022
pegfilgrastim
will be given at 6 mg subcutaneously (SC) at the end of the mesna infusion
doxorubicin hydrochloride
65 mg/m\^2 by continuous intravenous (IV) infusion over 7 days beginning on day 1
ifosfamide
9 g/m\^2 by continuous intravenous (IV) infusion over 6 days beginning on day 1 with mesna 10.5 g/m\^2 by continuous IV infusion over 7 days beginning on day 1
pegylated liposomal doxorubicin hydrochloride
45 mg/m2 intravenous (IV) Day 1, repeat every 28 days.
conventional surgery
The surgical procedure will be decided by the treating physician and independent of study participation
fludeoxyglucose F 18
FDG is a radioactive sugar equal to a uniform whole-body exposure of approximately 1.5 rem for each scan. Post-operative radiation therapy may be given according to institutional guidelines in patients felt to have close surgical margins.
Sinai Hospital of Baltimore, Baltimore
Masonic Cancer Center at University of Minnesota, Minneapolis
Masonic Cancer Center, University of Minnesota
OTHER