Age-Related Eye Disease Study 2 (AREDS2)

PHASE3CompletedINTERVENTIONAL
Enrollment

4,203

Participants

Timeline

Start Date

September 30, 2006

Primary Completion Date

October 31, 2012

Study Completion Date

October 31, 2012

Conditions
Age-related Macular DegenerationCataract
Interventions
DIETARY_SUPPLEMENT

Lutein/zeaxanthin

10 mg lutein and 2 mg zeaxanthin (1 tablet) Placebo-DHA/EPA (2 soft-gel capsules)

DIETARY_SUPPLEMENT

DHA/EPA

Placebo-lutein/zeaxanthin (1 tablet) 350 mg DHA and 650 mg EPA (2 soft-gel capsules)

DRUG

Lutein/zeaxanthin and DHA/EPA

10 mg lutein and 2 mg zeaxanthin (1 tablet) 350 mg DHA and 650 mg EPA (2 soft-gel capsules)

Trial Locations (91)

10003

New York Eye and Ear Infirmary, New York

10021

Manhattan Eye, Ear and Throat Hospital, New York

11563

Ophthalmic Consultants of Long Island, Lynbrook

11794

The Research Foundation of SUNY/Stony Brook, Stony Brook

12159

Retina Consultants, PLLC, Slingerlands

14642

University of Rochester Eye Institute, Rochester

15213

Retina Vitreous Consultants, Pittsburgh

University of Pittsburgh Medical Center, Pittsburgh

17011

Pennsylvania Retina Specialists, PC, Camp Hill

17033

Penn State M.S. Hershey Medical Center, Hershey

19104

Scheie Eye Institute, Philadelphia

19107

Wills Eye Hospital/Mid Atlantic Retina, Philadelphia

20815

The Retina Group of Washington, Chevy Chase

20892

National Eye Institute, Bethesda

21237

Elman Retina Group, Baltimore

21287

Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore

22031

The Retina Group of Washington, Fairfax

27157

Wake Forest University Eye Center, Winston-Salem

27599

UNC Department of Ophthalmology, Chapel Hill

27710

Duke University, Durham

28210

Charlotte Eye Ear Nose and Throat Associates, Charlotte

28803

Western Carolina Retinal Associates, Asheville

29204

Palmetto Retina Center, Columbia

29223

Carolina Retina Center, Columbia

30030

Georgia Retina, PC, Decatur

30322

Emory University Eye Center, Atlanta

32209

University of Florida, Jacksonville

33136

Bascom Palmer Eye Institute, Miami

33334

Retina Group of Florida, Fort Lauderdale

33880

Center for Retina and Macular Disease, Winter Haven

34239

Sarasota Retina Institute, Sarasota

35294

University of Alabama at Birmingham, Birmingham

37232

Vanderbilt Eye Institute, Nashville

37909

Southeastern Retina Associates, PC, Knoxville

38163

University of Tennessee, Memphis

40509

Retina Associates of Kentucky, Lexington

42001

Paducah Retinal Center, Paducah

43210

Ohio State University, Columbus

44106

Case Western Reserve University, Cleveland

44122

Retina Associates of Cleveland, Cleveland

44130

Retina Associates of Cleveland, Middleburg Heights

44505

Retina Associates of Cleveland, Youngstown

48073

Vision Research Foundation, Royal Oak

48201

Kresge Eye Institute, Detroit

48202

Henry Ford Health System - Eye Care Services, Detroit

49546

Vision Research Foundation, Grand Rapids

49686

Vision Research Foundation, Traverse City

52242

University of Iowa, Iowa City

53226

The Medical College of Wisconsin, Milwaukee

53705

University of Wisconsin, Madison

55905

Mayo Clinic, Rochester

60026

NorthShore University HealthSystems, Glenview

60426

Ingalls Memorial Hospital, Harvey

60611

Northwestern University, Chicago

60612

The University of Illinois, Chicago

63110

The Retina Institute, St Louis

Washington University School of Medicine, St Louis

64108

Eye Foundation of Kansas City, Kansas City

64111

Mid-America Retina Consultants, PA, Kansas City

65212

University Health Care - Mason Eye Institute, Columbia

72205

Jones Eye Institute - UAMS, Little Rock

73104

Dean McGee Eye Institute, Oklahoma City

75231

Texas Retina Associates, Dallas

75390

UT Southwestern Medical Center, Dallas

76012

Texas Retina Associates, Arlington

76508

Scott and White Memorial Hospital, Temple

77030

Baylor College of Medicine, Houston

Retina Consultants of Houston, Houston

79424

Texas Retina Associates, Lubbock

80027

Eldorado Retina Associates, PC, Louisville

80218

Colorado Retina Associates, Denver

84132

John Moran Eye Center, Salt Lake City

90033

Doheny Eye Institute, Los Angeles

90095

Jules Stein Eye Institute, Los Angeles

90211

Retina-Vitreous Associates Medical Group, Beverly Hills

92093

Shiley Eye Center - UCSD, La Jolla

92262

Southern California Desert Retina Consultants, MC, Palm Springs

92354

Loma Linda University, Loma Linda

94107

West Coast Retina Medical Group, Inc, San Francisco

94115

Pacific Eye Associates, San Francisco

94553

VA Northern California Health Care System, Martinez

95817

University of California, Davis, Sacramento

97210

Devers Eye Institute, Portland

Retina Northwest, PC, Portland

98383

Retina Center Northwest, Silverdale

06510

Yale University Eye Center, New Haven

02114

Massachusetts Eye and Ear Infirmary, Boston

Ophthalmic Consultants of Boston, Boston

08648

Delaware Valley Retina Associates, Lawrenceville

07103

UMDNJ, Newark

05401

Fletcher Allen Health Care, Burlington

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

collaborator

Office of Dietary Supplements (ODS)

NIH

collaborator

National Center for Complementary and Integrative Health (NCCIH)

NIH

lead

National Eye Institute (NEI)

NIH

NCT00345176 - Age-Related Eye Disease Study 2 (AREDS2) | Biotech Hunter | Biotech Hunter