NCT00339183 - Comparison of Treatment Effect of Chemotherapy With Panitumumab to Chemotherapy Alone | Biotech Hunter

Enrollment

1,186

Participants

Timeline

Start Date

June 30, 2006

Primary Completion Date

April 1, 2009

Study Completion Date

November 1, 2010

Conditions

Metastatic Colorectal Cancer

Interventions

DRUG

Panitumumab

Panitumumab was administered by IV infusion on Day 1 of each 14-day cycle, just before administration of FOLFIRI chemotherapy.

DRUG

FOLFIRI

FOLFIRI chemotherapy was initiated on Day 1 of each treatment cycle at the following starting doses: irinotecan 180 mg/m\^2, leucovorin 400 mg/m\^2 racemate (or 200 mg/m\^2 I-leucovorin), 5-FU bolus 400 mg/m\^2, 5-FU infusion 2400 mg/m\^2.