Combination Chemotherapy With or Without Rituximab in Treating Patients With Previously Treated Chronic Lymphocytic Leukemia

PHASE2CompletedINTERVENTIONAL
Enrollment

56

Participants

Timeline

Start Date

July 31, 2005

Study Completion Date

March 31, 2011

Conditions
Leukemia
Interventions
BIOLOGICAL

rituximab

DRUG

cyclophosphamide

DRUG

fludarabine phosphate

DRUG

mitoxantrone hydrochloride

Trial Locations (16)

B9 5SS

Birmingham Heartlands Hospital, Birmingham

FY3 8NR

Blackpool Victoria Hospital, Blackpool

CT2 7NR

Kent and Canterbury Hospital, Canterbury

SM5 1AA

St Helier Hospital, Carshalton

DA2 8DA

Darent Valley Hospital, Dartford Kent

ME7 5NY

Medway Maritime Hospital, Gillingham Kent

LS1 3EX

Leeds General Infirmary at Leeds Teaching Hospital NHS Trust, Leeds

LE1 5WW

Leicester Royal Infirmary, Leicester

L7 8XP

Royal Liverpool and Broadgreen Hospitals NHS Trust, Liverpool

ME16 9QQ

Maidstone Hospital, Maidstone

M20 4BX

Christie Hospital NHS Trust, Manchester

TR1 3LJ

Royal Cornwall Hospital, Truro, Cornwall

TN4 8AT

Kent and Sussex Hospital, Tunbridge Wells, Kent

ML2 0DP

Wishaw General Hospital, Wishaw

ML6 0JF

Monklands General Hospital, Airdrie

CF14 4XW

University Hospital of Wales, Cardiff

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Cancer Research UK

OTHER