S0530 Cytarabine and Clofarabine in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia

PHASE2CompletedINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

October 31, 2006

Primary Completion Date

December 31, 2008

Study Completion Date

January 31, 2013

Conditions
Leukemia
Interventions
DRUG

clofarabine

Induction: 40mg/m2/d; IV over 1 hr; days 1-5 Re-induction (if necessary): 40mg/m2/d; IV over 1 hr; days 1-5 Consolidation: 40mg/m2/d; IV over 1 hr; days 1-4

DRUG

cytarabine

Induction: 1g/m2/d; IV over 2 hrs; days 1-5 Re-induction (if necessary): 1g/m2/d; IV over 2 hrs; days 1-5 Consolidation: 1g/m2/d; IV over 2 hrs; days 1-4

Trial Locations (91)

14642

James P. Wilmot Cancer Center at University of Rochester Medical Center, Rochester

29425

Hollings Cancer Center at Medical University of South Carolina, Charleston

30033

Charles B. Eberhart Cancer Center at DeKalb Medical Center, Decatur

30045

Gwinnett Medical Center, Lawrenceville

30060

Kennestone Cancer Center at Wellstar Kennestone Hospital, Marietta

30106

WellStar Cobb Hospital, Austell

30309

Piedmont Hospital, Atlanta

30342

CCOP - Atlanta Regional, Atlanta

32806

M.D. Anderson Cancer Center at Orlando, Orlando

44131

Community Oncology Group at Cleveland Clinic Cancer Center, Independence

44195

Cleveland Clinic Taussig Cancer Center, Cleveland

44691

Cleveland Clinic - Wooster, Wooster

45177

Clinton Memorial Hospital, Wilmington

45385

Ruth G. McMillan Cancer Center at Greene Memorial Hospital, Xenia

45405

Grandview Hospital, Dayton

45406

Good Samaritan Hospital, Dayton

45409

David L. Rike Cancer Center at Miami Valley Hospital, Dayton

45415

Samaritan North Cancer Care Center, Dayton

45428

Veterans Affairs Medical Center - Dayton, Dayton

45429

CCOP - Dayton, Dayton

Charles F. Kettering Memorial Hospital, Kettering

45840

Blanchard Valley Medical Associates, Findlay

46107

St. Francis Hospital and Health Centers - Beech Grove Campus, Beech Grove

47374

Reid Hospital & Health Care Services, Richmond

59101

CCOP - Montana Cancer Consortium, Billings

Hematology-Oncology Centers of the Northern Rockies - Billings, Billings

Northern Rockies Radiation Oncology Center, Billings

St. Vincent Healthcare Cancer Care Services, Billings

59405

Frontier Cancer Center, Great Falls

Great Falls Clinic - Main Facility, Great Falls

59601

St. Peter's Hospital, Helena

59701

St. James Healthcare Cancer Care, Butte

59715

Bozeman Deaconess Cancer Center, Bozeman

59801

Community Medical Center, Missoula

59804

Guardian Oncology and Center for Wellness, Missoula

59807

Montana Cancer Center at St. Patrick Hospital and Health Sciences Center, Missoula

59901

Glacier Oncology, PLLC, Kalispell

Kalispell Medical Oncology at KRMC, Kalispell

Kalispell Regional Medical Center, Kalispell

60153

Cardinal Bernardin Cancer Center at Loyola University Medical Center, Maywood

66720

Cancer Center of Kansas, PA - Chanute, Chanute

67042

Cancer Center of Kansas, PA - El Dorado, El Dorado

Cancer Center of Kansas, PA - Salina, Salina

67068

Cancer Center of Kansas, PA - Kingman, Kingman

67114

Cancer Center of Kansas, PA - Newton, Newton

67124

Cancer Center of Kansas, PA - Pratt, Pratt

67152

Cancer Center of Kansas, PA - Wellington, Wellington

67156

Cancer Center of Kansas, PA - Winfield, Winfield

67208

Associates in Womens Health, PA - North Review, Wichita

Cancer Center of Kansas, PA - Medical Arts Tower, Wichita

67214

Cancer Center of Kansas, PA - Wichita, Wichita

CCOP - Wichita, Wichita

Via Christi Cancer Center at Via Christi Regional Medical Center, Wichita

Wesley Medical Center, Wichita

67357

Cancer Center of Kansas, PA - Parsons, Parsons

67401

Tammy Walker Cancer Center at Salina Regional Health Center, Salina

67801

Cancer Center of Kansas, PA - Dodge City, Dodge City

67901

Southwest Medical Center, Liberal

72205

Arkansas Cancer Research Center at University of Arkansas for Medical Sciences, Little Rock

76508

CCOP - Scott and White Hospital, Temple

77030

Baylor University Medical Center - Houston, Houston

Ben Taub General Hospital, Houston

Methodist Hospital, Houston

St. Luke's Texas Cancer Institute at St. Luke's Episcopal Hospital, Houston

Veterans Affairs Medical Center - Houston, Houston

82801

Welch Cancer Center at Sheridan Memorial Hospital, Sheridan

84112

Huntsman Cancer Institute at University of Utah, Salt Lake City

92868

Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center, Orange

98104

Fred Hutchinson Cancer Research Center, Seattle

Harborview Medical Center, Seattle

Minor and James Medical, PLLC, Seattle

98112

Group Health Central Hospital, Seattle

98122

Polyclinic First Hill, Seattle

98225

St. Joseph Cancer Center, Bellingham

98310

Olympic Hematology and Oncology, Bremerton

99202

Cancer Care Northwest - Spokane South, Spokane

99508

Providence Cancer Center, Anchorage

94305-5824

Stanford Cancer Center, Stanford

33612-9497

H. Lee Moffitt Cancer Center and Research Institute at University of South Florida, Tampa

30342-1611

Northside Hospital Cancer Center, Atlanta

30342-1701

Saint Joseph's Hospital of Atlanta, Atlanta

30274-2600

Southern Regional Medical Center, Riverdale

71315-3198

Tulane Cancer Center Office of Clinical Research, Alexandria

48109-0942

University of Michigan Comprehensive Cancer Center, Ann Arbor

59107-7000

Billings Clinic - Downtown, Billings

59807-7877

Montana Cancer Specialists at Montana Cancer Center, Missoula

45005-1066

Middletown Regional Hospital, Franklin

45373-1300

UVMC Cancer Care Center at Upper Valley Medical Center, Troy

98122-4307

Swedish Cancer Institute at Swedish Medical Center - First Hill Campus, Seattle

98195-6043

University Cancer Center at University of Washington Medical Center, Seattle

98801-2028

Wenatchee Valley Medical Center, Wenatchee

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

SWOG Cancer Research Network

NETWORK

NCT00337168 - S0530 Cytarabine and Clofarabine in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia | Biotech Hunter | Biotech Hunter