121
Participants
Start Date
June 30, 2006
Primary Completion Date
November 30, 2006
Study Completion Date
February 29, 2008
Laser Photocoagulation
Laser photocoagulation at baseline; If edema present at 12 weeks, can be treated with 2 intravitreal injections of 1.25 mg bevacizumab spaced 6 weeks apart
Bevacizumab
1.25 mg intravitreal injection of bevacizumab at baseline and 6 weeks
Bevacizumab
2.5 mg intravitreal injection of bevacizumab at baseline and 6 weeks
Bevacizumab
1.25 mg intravitreal injection of bevacizumab at baseline (sham injection at 6 weeks)
Bevacizumab
1.25 mg intravitreal injection of bevacizumab at baseline, laser photocoagulation at 3 weeks, and intravitreal injection of 1.25 mg bevacizumab at 6 weeks
Penn State College of Medicine, Hershey
Elman Retina Group, P.A., Baltimore
Retina Consultants of Delmarva, P.A., Salisbury
Wake Forest University Eye Center, Winston-Salem
Charlotte Eye, Ear, Nose and Throat Assoc., PA, Charlotte
Palmetto Retina Center, Columbia
Carolina Retina Center, Columbia
Southeast Retina Center, P.C., Augusta
Retina Vitreous Consultants, Fort Lauderdale
Central Florida Retina Institute, Lakeland
Southeastern Retina Associates, P.C., Knoxville
Paducah Retinal Center, Paducah
Retina Associates of Cleveland, Inc., Beachwood
Raj K. Maturi, M.D., P.C., Indianapolis
American Eye Institute, New Albany
Retina Center, PA, Minneapolis
Illinois Retina Associates, Joliet
Texas Retina Associates, Dallas
Charles A. Garcia, PA & Associates, Houston
Retina Research Center, Austin
Texas Retina Associates, Lubbock
West Texas Retina Consultants P.A., Abilene
Southern California Desert Retina Consultants, MC, Palm Springs
Loma Linda University Health Care, Dept. of Ophthalmology, Loma Linda
California Retina Consultants, Santa Barbara
Bay Area Retina Associates, Walnut Creek
Retina Northwest, PC, Portland
Casey Eye Institute, Portland
University of Washington Medical Center, Seattle
Retina and Vitreous Associates of Kentucky, Lexington
Maine Vitreoretinal Consultants, Bangor
Ophthalmic Consultants of Boston, Boston
Joslin Diabetes Center, Boston
Retina Consultants, Providence
Lead Sponsor
National Eye Institute (NEI)
NIH
Jaeb Center for Health Research
OTHER