91
Participants
Start Date
October 22, 2007
Primary Completion Date
December 31, 2016
Study Completion Date
September 30, 2025
Autologous Hematopoietic Stem Cell Transplantation
Undergo autologous PBSC resuce
Carboplatin
Given IV
Cisplatin
Given IV
Cyclophosphamide
Given IV
Etoposide
Given IV
Filgrastim
Given IV or SC
Laboratory Biomarker Analysis
Correlative studies
Leucovorin Calcium
Given IV or orally
Methotrexate
Given IV
Quality-of-Life Assessment
Ancillary studies
Thiotepa
Given IV
Vincristine Sulfate
Given IV
Sydney Children's Hospital, Randwick
The Children's Hospital at Westmead, Westmead
Royal Children's Hospital, Parkville
Princess Margaret Hospital for Children, Perth
Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
Memorial Sloan Kettering Cancer Center, New York
Montefiore Medical Center - Moses Campus, The Bronx
New York Medical College, Valhalla
NYU Langone Hospital - Long Island, Mineola
Stony Brook University Medical Center, Stony Brook
Roswell Park Cancer Institute, Buffalo
University of Rochester, Rochester
Children's Hospital of Pittsburgh of UPMC, Pittsburgh
Geisinger Medical Center, Danville
Children's Hospital of Philadelphia, Philadelphia
Saint Christopher's Hospital for Children, Philadelphia
Alfred I duPont Hospital for Children, Wilmington
Children's National Medical Center, Washington D.C.
Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore
Inova Fairfax Hospital, Falls Church
VCU Massey Comprehensive Cancer Center, Richmond
UNC Lineberger Comprehensive Cancer Center, Chapel Hill
Carolinas Medical Center/Levine Cancer Institute, Charlotte
Novant Health Presbyterian Medical Center, Charlotte
Prisma Health Richland Hospital, Columbia
Medical University of South Carolina, Charleston
BI-LO Charities Children's Cancer Center, Greenville
Greenville Cancer Treatment Center, Greenville
Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta
Memorial Health University Medical Center, Savannah
Nemours Children's Clinic-Jacksonville, Jacksonville
Nemours Children's Clinic - Pensacola, Pensacola
University of Florida Health Science Center - Gainesville, Gainesville
AdventHealth Orlando, Orlando
Arnold Palmer Hospital for Children, Orlando
Nemours Children's Clinic - Orlando, Orlando
Orlando Health Cancer Institute, Orlando
Nemours Children's Hospital, Orlando
Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood
University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami
Nicklaus Children's Hospital, Miami
Broward Health Medical Center, Fort Lauderdale
Saint Mary's Medical Center, West Palm Beach
Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa
Johns Hopkins All Children's Hospital, St. Petersburg
Lee Memorial Health System, Fort Myers
Golisano Children's Hospital of Southwest Florida, Fort Myers
Children's Hospital of Alabama, Birmingham
University of Alabama at Birmingham Cancer Center, Birmingham
Vanderbilt University/Ingram Cancer Center, Nashville
East Tennessee Childrens Hospital, Knoxville
University of Mississippi Medical Center, Jackson
Norton Children's Hospital, Louisville
University of Kentucky/Markey Cancer Center, Lexington
Nationwide Children's Hospital, Columbus
ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo
Mercy Children's Hospital, Toledo
Rainbow Babies and Childrens Hospital, Cleveland
Cleveland Clinic Foundation, Cleveland
Cincinnati Children's Hospital Medical Center, Cincinnati
Dayton Children's Hospital, Dayton
Ascension Saint Vincent Indianapolis Hospital, Indianapolis
C S Mott Children's Hospital, Ann Arbor
Michigan State University, East Lansing
Bronson Methodist Hospital, Kalamazoo
Kalamazoo Center for Medical Studies, Kalamazoo
Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids
University of Iowa/Holden Comprehensive Cancer Center, Iowa City
Children's Hospital of Wisconsin, Milwaukee
Marshfield Medical Center-Marshfield, Marshfield
Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis
University of Minnesota/Masonic Cancer Center, Minneapolis
Mayo Clinic in Rochester, Rochester
Sanford Broadway Medical Center, Fargo
Loyola University Medical Center, Maywood
Advocate Children's Hospital-Oak Lawn, Oak Lawn
Lurie Children's Hospital-Chicago, Chicago
Cardinal Glennon Children's Medical Center, St Louis
Washington University School of Medicine, St Louis
Mercy Hospital Saint Louis, St Louis
Children's Mercy Hospitals and Clinics, Kansas City
Tulane University School of Medicine, New Orleans
University of Arkansas for Medical Sciences, Little Rock
University of Oklahoma Health Sciences Center, Oklahoma City
Medical City Dallas Hospital, Dallas
Cook Children's Medical Center, Fort Worth
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston
Methodist Children's Hospital of South Texas, San Antonio
University of Texas Health Science Center at San Antonio, San Antonio
Driscoll Children's Hospital, Corpus Christi
Texas Tech University Health Sciences Center-Amarillo, Amarillo
Covenant Children's Hospital, Lubbock
Children's Hospital Colorado, Aurora
Saint Luke's Cancer Institute - Boise, Boise
Primary Children's Hospital, Salt Lake City
Phoenix Childrens Hospital, Phoenix
University of New Mexico Cancer Center, Albuquerque
Nevada Cancer Research Foundation NCORP, Las Vegas
Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas
Children's Hospital Los Angeles, Los Angeles
Cedars Sinai Medical Center, Los Angeles
Kaiser Permanente Downey Medical Center, Downey
Miller Children's and Women's Hospital Long Beach, Long Beach
Rady Children's Hospital - San Diego, San Diego
Loma Linda University Medical Center, Loma Linda
Children's Hospital of Orange County, Orange
Valley Children's Hospital, Madera
UCSF Medical Center-Parnassus, San Francisco
Sutter Medical Center Sacramento, Sacramento
University of California Davis Comprehensive Cancer Center, Sacramento
University of Hawaii Cancer Center, Honolulu
Legacy Emanuel Children's Hospital, Portland
Legacy Emanuel Hospital and Health Center, Portland
Oregon Health and Science University, Portland
Seattle Children's Hospital, Seattle
Mary Bridge Children's Hospital and Health Center, Tacoma
Providence Sacred Heart Medical Center and Children's Hospital, Spokane
Arkansas Children's Hospital, Little Rock
Connecticut Children's Medical Center, Hartford
Eastern Maine Medical Center, Bangor
Walter Reed National Military Medical Center, Bethesda
Tufts Children's Hospital, Boston
Dana-Farber Cancer Institute, Boston
Hackensack University Medical Center, Hackensack
Morristown Medical Center, Morristown
Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick
Newark Beth Israel Medical Center, Newark
Saint Joseph's Regional Medical Center, Paterson
Overlook Hospital, Summit
Sanford USD Medical Center - Sioux Falls, Sioux Falls
University of Vermont and State Agricultural College, Burlington
Naval Medical Center - Portsmouth, Portsmouth
Alberta Children's Hospital, Calgary
British Columbia Children's Hospital, Vancouver
CancerCare Manitoba, Winnipeg
IWK Health Centre, Halifax
McMaster Children's Hospital at Hamilton Health Sciences, Hamilton
Kingston Health Sciences Centre, Kingston
Children's Hospital of Eastern Ontario, Ottawa
Hospital for Sick Children, Toronto
The Montreal Children's Hospital of the MUHC, Montreal
Centre Hospitalier Universitaire Sainte-Justine, Montreal
CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Québec
San Jorge Children's Hospital, San Juan
National Cancer Institute (NCI)
NIH
Children's Oncology Group
NETWORK