NCT00334594 - Pemetrexed Disodium and Cisplatin Followed by Surgery With or Without Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma | Biotech Hunter

Enrollment

153

Participants

Timeline

Start Date

November 14, 2005

Primary Completion Date

March 26, 2014

Study Completion Date

January 23, 2018

Conditions

Malignant Mesothelioma

Interventions

DRUG

Cisplatin

Cisplatin 75 mg/m2 i.v. over approximately 2 hours on day 1 every 21 days

DRUG

Pemetrexed

Pemetrexed 500 mg/m2 i.v. over approximately 10 minutes on day 1 every 21 days

PROCEDURE

Therapeutic conventional surgery

Extrapleural pneumonectomy

RADIATION

Radiotherapy

CTV1 will receive 45 or 46 Gy. CTV2 will be treated up to a total dose of 55,9 to 56,2 Gy.

Trial Locations (13)

3004

Spital Tiefenau, Bern

3600

SpitalSTS AG Simmental-Thun-Saanenland, Thun

D-79106

Universitaetsklinikum Freiburg, Freiburg im Breisgau

CH-5001

Kantonsspital Aarau, Aarau

CH-5404

Kantonsspital Baden, Baden

CH-4031

Universitaetsspital-Basel, Basel

CH-3010

Inselspital Bern, Bern

CH-4101

Kantonsspital Bruderholz, Bruderholz

CH-7000

Kantonsspital Graubuenden, Chur

CH-1011

Centre Hospitalier Universitaire Vaudois, Lausanne

CH-4600

Kantonsspital Olten, Olten

CH-9007

Kantonsspital - St. Gallen, Sankt Gallen

CH-8091

UniversitaetsSpital Zuerich, Zurich

All Listed Sponsors

lead

Swiss Cancer Institute

OTHER