8
Participants
Start Date
September 30, 2004
Primary Completion Date
August 31, 2007
Study Completion Date
August 31, 2007
dexmedetomidine
Dexmedetomidine (delivered by a computer-controlled IV infusion to target a plasma concentration of 0.6 ng/mL) will be given during controlled hypothermia
buspirone
Buspirone, 60 mg orally, will be given during controlled hypothermia.
Bus and Dex
the combination of 60 mg buspirone and dexmedetomidine (target plasma concentration of 0.6 ng/mL) will be given during controlled hypothermia
Control
No drugs given during controlled hypothermia
Outcomes Research Institute, University of Louisville, Louisville
The Cleveland Clinic
OTHER