A Study of Bevacizumab (Avastin) in Women With HER2 Negative Metastatic Breast Cancer

PHASE3CompletedINTERVENTIONAL
Enrollment

736

Participants

Timeline

Start Date

March 31, 2006

Primary Completion Date

October 31, 2007

Study Completion Date

October 31, 2013

Conditions
Breast Cancer
Interventions
DRUG

Docetaxel

Docetaxel was supplied in 2 vials, 1 containing docetaxel and 1 containing a solvent, for intravenous infusion.

DRUG

Placebo to bevacizumab

Placebo to bevacizumab was supplied as a sterile liquid for intravenous infusion in single-use vials.

DRUG

Bevacizumab

Bevacizumab was supplied as a sterile liquid for intravenous infusion in single-use vials.

Trial Locations (114)

100

Taipei

114

Taipei

813

Kaohsiung City

1000

Brussels

1090

Vienna

2050

Camperdown

2145

Westmead

2196

Sandton

2610

Wilrijk

3065

Fitzroy

3128

Box Hill

3135

Ringwood East

4066

Auchenflower

4840

Vöcklabruck

5011

Adelaide

5020

Salzburg

6000

Perth

7000

Chur

8036

Graz

10400

Bangkok

10700

Bangkok

13900

Biella

14076

Caen

14195

Berlin

20246

Hamburg

21079

Dijon

21100

Mexicali

22185

Lund

23007

Jaén

24047

Treviglio

25030

Besançon

28041

Madrid

29010

Málaga

32657

Lemgo

33076

Bordeaux

33100

Udine

34100

Trieste

34298

Montpellier

40002

Khon Kaen

40138

Bologna

40225

Düsseldorf

41100

Modena

43100

Parma

50009

Kaunas

54290

Trier

58185

Linköping

59020

Lille

60389

Frankfurt am Main

60596

Frankfurt

62100

Macerata

63011

Clermont-Ferrand

64380

Monterrey

69120

Heidelberg

70376

Stuttgart

72076

Tübingen

72530

Puebla City

81675

München

85000

Obregón

89075

Ulm

90185

Umeå

91054

Erlangen

91522

Ansbach

94805

Villejuif

97500

Mérida

98030

Taormina

100021

Beijing

74605-070

Goiânia

31190-131

Belo Horizonte

90610-000

Porto Alegre

88034-000

Florianópolis

14784-400

Barretos

01509-010

São Paulo

T2N 4N2

Calgary

T6G 1Z2

Edmonton

V5Z 4E6

Vancouver

B3H 1V7

Halifax

P3E 5J1

Greater Sudbury

K1H 8L6

Ottawa

M4N 3M5

Toronto

H4J 1C5

Montreal

G1S 4L8

Québec

06120

Halle

07743

Jena

08660

Vilnius

06760

Mexico City

6131 BK

Sittard

3582 KE

Utrecht

83-0669

Panama City

31-826

Krakow

10-513

Olsztyn

60-569

Poznan

02-781

Warsaw

53-413

Wroclaw

3000-075

Coimbra

1099-023

Lisbon

022328

Bucharest

0002

Pretoria

120-752

Seoul

135-710

Seoul

138-736

Seoul

08003

Barcelona

08035

Barcelona

08036

Barcelona

08907

Barcelona

BH7 7DW

Bournemouth

CB2 2QQ

Cambridge

EH4 2XU

Edinburgh

LS16 5WW

Leeds

LS9 7TF

Leeds

SE1 7EH

London

M20 4BX

Manchester

HA6 2RN

Middlesex

NE7 7DN

Newcastle upon Tyne

TR1 3LJ

Truro

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY

NCT00333775 - A Study of Bevacizumab (Avastin) in Women With HER2 Negative Metastatic Breast Cancer | Biotech Hunter | Biotech Hunter