Weekly Subcutaneous Alemtuzumab and Rituximab for Relapsed CLL

PHASE1CompletedINTERVENTIONAL
Enrollment

29

Participants

Timeline

Start Date

May 31, 2006

Primary Completion Date

January 31, 2013

Study Completion Date

January 31, 2014

Conditions
Chronic Lymphocytic Leukemia
Interventions
DRUG

Rituximab

Given intravenously on day 1 of every week for eight weeks (or 16 weeks)

DRUG

Alemtuzumab

Drug: Alemtuzumab Dosage will vary during Phase I of trial: Given intravenously on days 1, 3, and 5 for weeks one and two, on days 1 and 4 for weeks three and four and on day 1 for weeks five through eight. Participants may receive either one eight-week course of treatment or two eight-week courses of treatment (16 weeks).

Trial Locations (2)

02115

Dana-Farber Cancer Institute, Boston

02215

Beth Israel Deaconess Medical Center, Boston

All Listed Sponsors
collaborator

Genzyme, a Sanofi Company

INDUSTRY

lead

Dana-Farber Cancer Institute

OTHER

NCT00330252 - Weekly Subcutaneous Alemtuzumab and Rituximab for Relapsed CLL | Biotech Hunter | Biotech Hunter