Natural Killer Cells Plus IL-2 Following Chemotherapy to Treat Advanced Melanoma or Kidney Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

May 31, 2006

Primary Completion Date

July 31, 2007

Study Completion Date

April 30, 2009

Conditions
Metastatic MelanomaMetastatic Kidney Cancer
Interventions
DRUG

Natural Killer (NK) Lymphocytes

Thirty minutes infusion of natural killer (NK) cells 2 days after last dose of chemotherapy.

BIOLOGICAL

IL-2

IL-2 720,000 IU/kg/intravenous every 8 hours for up to 5 days.

DRUG

Cyclophosphamide

Cyclophosphamide 60 mg/kg/day intravenous on days -8 and -7.

DRUG

Fludarabine

Fludarabine 25 mg/m\^2 day intravenous on days -6 through -2.

Trial Locations (1)

20892

National Cancer Institute (NCI), Bethesda

All Listed Sponsors
lead

National Cancer Institute (NCI)

NIH

NCT00328861 - Natural Killer Cells Plus IL-2 Following Chemotherapy to Treat Advanced Melanoma or Kidney Cancer | Biotech Hunter | Biotech Hunter