Using Intensity Modulated Radiation Therapy (IMRT) for Brain Metastases

PHASE1CompletedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

October 31, 2005

Primary Completion Date

July 31, 2009

Study Completion Date

June 30, 2011

Conditions
Neoplasm Metastasis
Interventions
RADIATION

Intensity-Modulated Radiotherapy (IMRT)

"The duration of radiation therapy will be total of 3 weeks. During the first week, all patients will be treated initially with whole brain radiation therapy (WBRT) at 2.5Gy per fraction daily 5 days a week to a dose of 12.5Gy. This will be delivered through parallel-opposed fields to cover the entire cranial contents.~For the remaining 2 weeks, patients will be treated using intensity-modulated radiation therapy (IMRT) technology such that a higher dose can be delivered to the tumor. IMRT is capable of generating complex 3-D dose distribution to conform closely to the target volume by modulating the radiation beam. This process is based on the inverse method of treatment planning to optimize radiation dose to tumor target coverage and normal tissue sparing."

Trial Locations (1)

19107

Thomas Jefferson University, Philadelphia

All Listed Sponsors
lead

Sidney Kimmel Cancer Center at Thomas Jefferson University

OTHER

NCT00328575 - Using Intensity Modulated Radiation Therapy (IMRT) for Brain Metastases | Biotech Hunter | Biotech Hunter