Steroids for Corneal Ulcers Trial

PHASE4CompletedINTERVENTIONAL
Enrollment

500

Participants

Timeline

Start Date

September 30, 2006

Primary Completion Date

February 28, 2011

Study Completion Date

December 31, 2012

Conditions
Corneal UlcerEye Infections, Bacterial
Interventions
DRUG

Antibiotics

moxifloxacin 0.5% every one hour for 48 hours while awake and then every 2 hours until re-epithelialization

DRUG

Topical corticosteroid

prednisolone phosphate 1% with preservative four times a day for 1 week, then twice a day for 1 week, and finally once a day for 1 week

DRUG

Placebo

0.9% NaCl and preservative (same as in steroid) four times a day for 1 week, then twice a day for 1 week, and finally once a day for 1 week

Trial Locations (5)

94143

Proctor Foundation, UCSF, San Francisco

03756

Dartmouth Hitchcock Medical Center, Lebanon

Unknown

Aravind Eye Hospital, Coimbatore

Aravind Eye Hospital, Tirunelveli

625 020

Aravind Eye Hospital, Madurai

All Listed Sponsors
collaborator

Aravind Eye Hospitals, India

OTHER

collaborator

Dartmouth-Hitchcock Medical Center

OTHER

collaborator

National Eye Institute (NEI)

NIH

lead

Thomas M. Lietman

OTHER

NCT00324168 - Steroids for Corneal Ulcers Trial | Biotech Hunter | Biotech Hunter