Trachoma Amelioration in Northern Amhara (TANA)

PHASE4CompletedINTERVENTIONAL
Enrollment

33,000

Participants

Timeline

Start Date

June 30, 2006

Primary Completion Date

November 30, 2009

Study Completion Date

May 31, 2014

Conditions
TrachomaChlamydia
Interventions
DRUG

Mass treatment with oral azithromycin to an entire community

For baseline and follow-up surveys prior to azithromycin distribution, a stratified random sample from two age groups will be chosen: 1) 60 study participants younger than 10 years old and 2) 60 study participants aged 10 years and above. Clinical examination will be performed and conjunctival swabs will be taken from all the study participants. For study arm C and D, nasopharyngeal swabs will be collected from 10 randomly selected children among the 60 participants under 10 who were recruited for conjunctival swabbing. Then a single dose of azithromycin will be distributed according to study design: in tablet form for adults; a weight-adjusted tablet dose for children ages 8-10; and pediatric suspension for children ages 1 - 7.

Trial Locations (1)

Unknown

Carter Center, Ethiopia, Addis Ababa

All Listed Sponsors
lead

University of California, San Francisco

OTHER

NCT00322972 - Trachoma Amelioration in Northern Amhara (TANA) | Biotech Hunter | Biotech Hunter