A Study of the Safety and Efficacy of Memantine in Moderate to Severe Alzheimer's Disease

PHASE3CompletedINTERVENTIONAL
Enrollment

677

Participants

Timeline

Start Date

June 30, 2005

Primary Completion Date

October 31, 2007

Study Completion Date

January 31, 2008

Conditions
Dementia of the Alzheimer's Type
Interventions
DRUG

memantine ER

28mg(7mg capsules) once daily and oral administration for 24 weeks.

DRUG

Placebo

Matching placebo oral administration once daily.

Trial Locations (83)

10605

Forest Investigative Site 004, White Plains

12205

Forest Investigative Site 048, Albany

14000

Forest Investigative Site 202, Mexico City

14050

Forest Investigative Site 207, Mexico City

14215

Forest Investigative Site 006, Buffalo

15601

Forest Investigative Site 032, Greensburg

19046

Forest Investigative Site 018, Jenkintown

20230

Forest Investigative Site 206, Aguascalientes

23229

Forest Investigative Site 013, Richmond

25000

Forest Investigative Site 212, Saltillo

30078

Forest Investigative Site 009, Snellville

32806

Forest Investigative Site 068, Orlando

33009

Forest Investigative Site 043, Hallandale

Forest Investigative Site 044, Hallandale

33137

Forest Investigative Site 001, Miami

33161

Forest Investigative Site 034, North Miami

33410

Forest Investigative Site 038, Palm Beach Gardens

33426

Forest Investigative Site 052, Boynton Beach

33445

Forest Investigative Site 070, Delray Beach

33486

Forest Investigative Site 021, Boca Raton

33617

Forest Investigative Site 028, Tampa

33709

Forest Investigative Site 008, St. Petersburg

33912

Forest Investigative Site 065, Fort Myers

37000

Forest Investigative Site 211, León

43623

Forest Investigative Site 012, Toledo

44610

Forest Investigative Site 205, Guadalajara

Forest Investigative Site 208, Monterrey

45200

Forest Investigative Site 203, Zapopan

45459

Forest Investigative Site 027, Centerville

49048

Forest Investigative Site 045, Kalamazoo

60435

Forest Investigative Site 069, Joliet

63104

Forest Investigative Site 014, Saint Loius

64710

Forest Investigative Site 204, Monterrey

78090

Forest Investigative Site 210, San Luis Potosí City

78229

Forest Investigative Site 017, San Antonio

78757

Forest Investigative Site 041, Austin

80262

Forest Investigative Site 002, Denver

80400

Forest Investigative Site 213, Culiacán

85004

Forest Investigative Site 010, Phoenix

92626

Forest Investigative Site 062, Costa Mesa

92705

Forest Investigative Site 071, Santa Ana

93720

Forest Investigative Site 050, Fresno

94118

Forest Investigative Site 024, San Francisco

97210

Forest Investigative Site 020, Portland

98405

Forest Investigative Site 026, Tacoma

07742

Forest Investigative Site 064, Long Branch

07960

Forest Investigative Site 011, Morristown

08903

Forest Investigative Site 003, New Brunswick

02914

Forest Investigative Site 067, East Providence

B1828CKR

Forest Investigative Site 103, Banfield

1419HDN

Forest Investigative Site 102, Buenos Aires

C1062ABF

Forest Investigative Site 118, Buenos Aires

C1117ABE

Forest Investigative Site 109, Buenos Aires

C1122AAJ

Forest Investigative Site 104, Buenos Aires

C1126AAB

Forest Investigative Site 108, Buenos Aires

C1181ACH

Forest Investigative Site 114, Buenos Aires

C1209AAB

Forest Investigative Site 106, Buenos Aires

C1405CNF

Forest Investigative Site 119, Buenos Aires

C1413FWO

Forest Investigative Site 122, Buenos Aires

C1419AHN

Forest Investigative Site 107, Buenos Aires

C1425AGP

Forest Investigative Site 111, Buenos Aires

C1425BPK

Forest Investigative Site 121, Buenos Aires

C1428AQK

Forest Investigative Site 115, Buenos Aires

Forest Investigative Site 116, Buenos Aires

B1900AVG

Forest Investigative Site 105, La Plata

C1824IBR

Forest Investigative Site 123, Lanús

X5000ALB

Forest Investigative Site 112, Córdoba

X5004AOA

Forest Investigative Site 124, Córdoba

M5500HYF

Forest Investigative Site 110, Mendoza

M5504FMI

Forest Investigative Site 125, Mendoza

S2000DSV

Forest Investigative Site 113, Rosario

S3000FWO

Forest Investigative Site 120, Santa Fe

Unknown

Forest Investigative Site 302, Antofagasta

Forest Investigative Site 308, Coquimbo

Forest Investigative Site 301, Las Condes

Forest Investigative Site 309, Las Condes

Forest Investigative Site 303, Providencia

Forest Investigative Site 310, Providencia

Forest Investigative Site 313, Recoleta

Forest Investigative Site 305, San Ramón

Forest Investigative Site 304, Santiago

Forest Investigative Site 312, Santiago

Forest Investigative Site 306, Valdivia

Sponsors
All Listed Sponsors
lead

Forest Laboratories

INDUSTRY