Comparison of Aripiprazole and Risperidone for the Treatment of People With First-Episode Psychosis

PHASE4CompletedINTERVENTIONAL
Enrollment

198

Participants

Timeline

Start Date

December 31, 2005

Primary Completion Date

December 31, 2014

Study Completion Date

December 31, 2015

Conditions
Schizophrenia
Interventions
DRUG

Aripiprazole

The dosage for aripiprazole will be 5 mg to 30 mg per day in capsule form. The dose of aripiprazole will be based on the participant's clinical improvement and side effects, which will be evaluated weekly for the first 4 weeks and then every 2 weeks until the 12th week and then monthly until study end.

DRUG

Risperidone

The dosage for risperidone will be 1 mg to 6 mg per day in capsule form. The dose of risperidone will be based on the participant's clinical improvement and side effects, which will be evaluated weekly for the first 4 weeks, then every 2 weeks until the 12th week, and then monthly until the study end.

Trial Locations (1)

11004

The Zucker Hillside Hospital, Glen Oaks

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

Northwell Health

OTHER