NCT00320099View on ClinicalTrials.gov

Combination of Corticotherapy and Intensive Insulin Therapy for Septic Shock

PHASE3CompletedINTERVENTIONAL
Enrollment

508

Participants

Timeline

Start Date

January 31, 2006

Primary Completion Date

January 31, 2009

Study Completion Date

February 28, 2009

Conditions
Septic Shock
Interventions
DRUG

recombinant human insulin

intensive insulin therapy as a continuous infusion to maintain blood glucose levels between 4 and 6 mmol/l

DRUG

hydrocortisone

50 mg as iv bolus every 6 hours for 7 days

DRUG

fludrocortisone

50 µg once a day via a nasogastric tube for seven days

DRUG

Hydrocortisone

hydrocortisone 50mg q6 for 7 days

Trial Locations (8)

75

Hôpital Saint Louis, Paris

93

Hôpital Delafontaine, Saint-Denis

Unknown

Hôpital Avicenne, Bobigny

Hôpital Jean Verdier, Bondy

CHU Grenoble, Grenoble

Hôpital central, Nancy

Hôpital Bichat Claude Bernard, Paris

hôpital Cochin, Paris

All Listed Sponsors
collaborator

Assistance Publique - Hôpitaux de Paris

OTHER

lead

University of Versailles

OTHER

NCT00320099 - Combination of Corticotherapy and Intensive Insulin Therapy for Septic Shock | Biotech Hunter | Biotech Hunter