NCT00312000 - Sequential Versus Combination Chemotherapy in Advanced Colorectal Carcinoma | Biotech Hunter

Enrollment

820

Participants

Timeline

Start Date

January 31, 2003

Primary Completion Date

February 28, 2006

Study Completion Date

December 31, 2006

Conditions

Advanced Colorectal Cancer

Interventions

DRUG

capecitabine-irinotecan

"1. st line capecitabine 1250 mg/m2 orally b.i.d. on day 1-14~2. nd line q 3 w irinotecan 350 mg/m2 IV infusion on day 1"

DRUG

capecitabine+irinotecan (1st line)

q 3 w irinotecan 250 mg/m2 IV infusion in 30 minutes on day 1 2 hours after discontinuation of the infusion followed by capecitabine 1000 mg/m2 orally b.i.d. on day 1-14