First Line Chemotherapy Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC)

PHASE2CompletedINTERVENTIONAL
Enrollment

218

Participants

Timeline

Start Date

March 31, 2006

Primary Completion Date

July 31, 2009

Study Completion Date

July 31, 2009

Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG

enzastaurin

1125-1200 milligrams (mg) loading dose then 500 mg, oral, daily, until disease progression

DRUG

pemetrexed

500 milligrams per square meter (mg/m\^2), intravenous (IV), once every (q) 21 days, six 21 day cycles or progressive disease

DRUG

docetaxel

75 mg/m\^2, IV, q 21 days, six 21 day cycles or progressive disease

DRUG

carboplatin

Area under the curve (AUC) 6, IV, q 21 days, six 21 day cycles or progressive disease

Trial Locations (4)

27215

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Burlington

27599

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Chapel Hill

29210

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Columbia

77060

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Houston

All Listed Sponsors
lead

Eli Lilly and Company

INDUSTRY

NCT00308750 - First Line Chemotherapy Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC) | Biotech Hunter | Biotech Hunter