NCT00307723 - Study of Bevacizumab in Combination With 5-FU, Oxaliplatin and External Beam Radiation Followed by Gemcitabine and Bevacizumab for Locally Advanced Pancreatic Cancer | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

May 31, 2006

Primary Completion Date

August 31, 2007

Study Completion Date

July 31, 2009

Conditions

Pancreatic CancerPancreatic Ductal Adenocarcinoma

Interventions

DRUG

bevacizumab

Intravenously on days 1, 15 and 29 of the first cycle. Intravenously on days 1, 15 of each 28-day cycles for cycles 2-5.

DRUG

5-Fluorouracil

Continuous infusion on days 1-5, 8-12, 15-19, 22-26, 29-33 and 36-38 of cycle one.

DRUG

Oxaliplatin

Intravenously on dasy 1, 8, 15, 22, 29, 36 of cycle one.

DRUG

gemcitabine

Intravenously on days 1, 8, 25 of every 28-day cycle for cycles 2-5.

PROCEDURE

External Beam Radiation Therapy

Monday through Friday ending on day 38 of cycle 1