1,230
Participants
Start Date
May 31, 2005
Primary Completion Date
December 31, 2006
Study Completion Date
October 31, 2011
Placebo; Ustekinumab (CNTO 1275) 45 or 90 mg
Placebo at Weeks 0 and 4 and blinded SC injections of ustekinumab, 45 or 90 mg, at Weeks 12 and 16; followed by a dosing regimen to be determined by patient's response status for Weeks 28 to 52; followed by unblinded dosing that may be adjusted at the investigator's discretion for Weeks 52 to 264
Ustekinumab (CNTO 1275) 45 mg
Ustekinumab, 45 mg, at Weeks 0 and 4 and every 12 weeks for Weeks 16 to 28. Followed by a dosing regimen to be determined by patient's response status for Weeks 28 to 52; followed by unblinded dosing that may be adjusted at the investigator's discretion for Weeks 52 to 264
Ustekinumab (CNTO 1275) 90 mg
Ustekinumab, 90 mg, at Weeks 0 and 4 and every 12 weeks for Weeks 16 to 28. Followed by a dosing regimen to be determined by patient's response status for Weeks 28 to 52; followed by unblinded dosing that may be adjusted at the investigator's discretion for Weeks 52 to 264
Birmingham
Little Rock
La Jolla
Los Angeles
San Diego
Jacksonville
Miami
Normal
Skokie
Indianapolis
Louisville
Andover
Boston
Port Huron
St Louis
Las Vegas
New Brunswick
New York
Winston-Salem
Cleveland
Portland
Philadelphia
Plymouth Meeting
Mt. Pleasant
Nashville
Houston
San Antonio
Salt Lake City
Graz
Innsbruck
Vienna
Calgary
Edmonton
Surrey
Vancouver
Moncton
Halifax
Barrie
Hamilton
London
North Bay
Toronto
Waterloo
Windsor
Montreal
Sainte-Foy
Sherbrooke
Nice
Berlin
Brandenburg
Dresden
Erlangen
Frankfurt
Hamburg
Kiel
Mainz
München
Geneva
Zurich
London
Salford
Southampton Trials Carried Out
Centocor Research & Development, Inc.
INDUSTRY