A Study to Evaluate Rituximab in Combination With Methotrexate in Methotrexate-Naive Patients With Active Rheumatoid Arthritis

PHASE3CompletedINTERVENTIONAL

Enrollment

755

Participants

Timeline

Start Date

January 31, 2006

Primary Completion Date

September 30, 2008

Study Completion Date

July 31, 2013

Conditions

Rheumatoid Arthritis

Interventions

DRUG

folate

Intravenous repeating dose

DRUG

methotrexate

Oral or parenteral repeating dose

DRUG

methylprednisolone

Intravenous repeating dose

DRUG

placebo

Intravenous repeating dose

DRUG

rituximab

Intravenous repeating dose