High-Dose Versus Standard-Dose Oseltamivir to Treat Severe Influenza and Avian Influenza

PHASE2CompletedINTERVENTIONAL
Enrollment

326

Participants

Timeline

Start Date

February 28, 2006

Primary Completion Date

January 31, 2010

Study Completion Date

January 31, 2010

Conditions
InfluenzaAvian InfluenzaSevere Influenza
Interventions
DRUG

Oseltamivir

Oseltamivir is a sialic acid analogue that potently and specifically inhibits the viral neuraminidases by competitively and reversibly interacting with the active enzyme site of influenza A and B viruses. Oseltamivir will be administered orally in standard formulations (capsules for adults and children at least 15 years of age; suspension for children younger than 15 years).

Trial Locations (12)

Unknown

Changi General Hospital, Singapore

National University Hospital, National University of Singapore, Singapore

Tan Tock Seng Hospital, Singapore

Queen Sirikit National Institute of Child Health, Bangkok

Siriraj Hospital Mahidol University, Bangkok

Bamrasnaradura Infectious Disease Institute, Nonthaburi

Chest Disease Institute, Nonthaburi

National Hospital of Pediatrics, Hanoi

National Institute fof Infectious and Tropical Diseases, Hanoi

Children's Hospital #1, Ho Chi Minh City

Hospital for Tropical Diseases, Ho Chi Minh City

Pediatric Hospital #2, Ho Chi Minh City

All Listed Sponsors
collaborator

Wellcome Trust

OTHER

collaborator

World Health Organization

OTHER

collaborator

University of Oxford

OTHER

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT00298233 - High-Dose Versus Standard-Dose Oseltamivir to Treat Severe Influenza and Avian Influenza | Biotech Hunter | Biotech Hunter