NCT00297830 - Zoledronic Acid Versus Alendronate for Prevention of Bone Loss After Organ Transplantation | Biotech Hunter

Enrollment

111

Participants

Timeline

Start Date

November 30, 2005

Primary Completion Date

April 30, 2010

Study Completion Date

January 31, 2014

Conditions

Heart TransplantationLiver TransplantationBone Resorption

Interventions

DRUG

Zoledronic acid

Drug is administered through 5 mg intravenous infusion over 20 minutes

DRUG

Alendronate

Alendronate 70 mg will be taken once a week in the morning at least 30-60 minutes before first meal

OTHER

Placebo Zoledronic Acid

Infusion of placebo zoledronic acid during the first 5 weeks after transplantation

OTHER

Placebo Alendronate

Placebo alendronate 70 mg once weekly

Trial Locations (1)

Columbia University Medical Center, New York