Gradual vs. Abrupt Cessation Treatment for Smoking

PHASE2CompletedINTERVENTIONAL
Enrollment

750

Participants

Timeline

Start Date

January 31, 2006

Primary Completion Date

February 29, 2008

Study Completion Date

February 29, 2008

Conditions
Smoking Cessation
Interventions
BEHAVIORAL

Reduction Phone Counseling

Counseling of smokers to undergo gradual reduction in cigarettes per day prior to quit date. This includes 5 counseling calls: 3 calls focused on reduction prior to the quit date, 1 call two days prior to the quit date to discuss common strategies for preparing to quit, and 1 call two days after the quit date to discuss relapse prevention. Telephone counseling also discusses the proper use of nicotine lozenges during reduction and after the quit date.

BEHAVIORAL

Abrupt Phone Counseling

Counseling of smokers to set a quit date and not change cigarettes per day prior to quit date. This includes 5 counseling calls: 1 to set a quit date, 1 two days prior to the quit date to discuss common strategies for preparing to quit, and 3 after the quit date to discuss relapse prevention. Telephone counseling also discusses the proper use of nicotine lozenges after the quit date.

BEHAVIORAL

Minimal Abrupt Phone Counseling

Minimal counseling to mimic intervention at a primary care office. This includes 2 counseling calls: 1 to set a quit date and 1 two days after the quit date to discuss relapse prevention. Telephone counseling also discusses the proper use of nicotine lozenges after the quit date.

DRUG

Pre-Quit Nicotine Lozenges

"2 mg lozenges for participants usually smoke their first cigarette more than 30 minutes after awaking.~4 mg lozenge for participants who usually smoke their first cigarette less than 30 minutes after awaking.~Replace each forgone cigarette during reduction with one lozenge. Use additional lozenges to combat cravings to smoke."

DRUG

Post-Quit Nicotine Lozenges

"2 mg lozenges for participants usually smoke their first cigarette more than 30 minutes after awaking.~4 mg lozenge for participants who usually smoke their first cigarette less than 30 minutes after awaking.~Replace each forgone cigarette while abstinent with one lozenge. Use additional lozenges to combat cravings to smoke."

Trial Locations (1)

05401

University of Vermont Human Behavioral Pharmacology Lab, Burlington

All Listed Sponsors
collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

University of Vermont

OTHER

NCT00297492 - Gradual vs. Abrupt Cessation Treatment for Smoking | Biotech Hunter | Biotech Hunter