45
Participants
Start Date
November 3, 2004
Primary Completion Date
June 30, 2011
Study Completion Date
December 31, 2013
Zoledronic Acid
Zoledronic acid is a new, highly potent, heterocyclic nitrogen-containing third generation bisphosphonate that has demonstrated 40- to 850- fold greater potency than pamidronate in preclinical models of bone resorption. The mechanism of action of nitrogen-containing bisphosphonates such as pamidronate and zoledronic acid appears to involve inhibition of the mevalonate pathway
University of California, San Francisco, San Francisco
Collaborators (1)
Novartis
INDUSTRY
University of California, San Francisco
OTHER