Enzastaurin Versus Lomustine in Glioblastoma

PHASE3CompletedINTERVENTIONAL
Enrollment

397

Participants

Timeline

Start Date

January 31, 2006

Primary Completion Date

August 31, 2007

Study Completion Date

May 31, 2014

Conditions
Glioblastoma
Interventions
DRUG

enzastaurin

1125 mg loading dose then 500 mg, oral, daily, 6 week cycles until PD

DRUG

lomustine

100-130 mg/m2, oral once, every 6 weeks until PD

Trial Locations (98)

1200

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2065

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2170

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3084

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4000

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4066

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5020

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6009

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8036

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10021

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10126

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11640

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13385

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14226

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14269

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15232

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19718

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20133

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20892

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21231

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22329

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22908

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27157

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28040

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30322

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33006

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33612

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37203

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38138

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40139

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43210

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44280

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46014

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48202

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52140

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52242

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53792

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54035

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55455

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55905

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60611

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61615

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63110

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64060

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65203

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66160

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69120

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69395

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72076

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75013

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75246

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77030

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78258

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79106

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79410

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80010

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80131

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81377

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84132

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85100

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85724

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86000

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87106

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87505

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89135

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94143

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94704

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96813

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98195

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02114

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03756

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A-4020

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A-1100

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B-3000

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N6A 4L6

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K1H 1C4

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M5G 2M9

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D-53105

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01307

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400 012

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110 029

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632 004

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00128

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1105 AZ

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6229 HX

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3075 EA

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2512 VA

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20-950

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02-781

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08915

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08907

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BS2 8ED

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CB2 2QQ

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EH4 2XU

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G11 6NT

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All Listed Sponsors
lead

Eli Lilly and Company

INDUSTRY

NCT00295815 - Enzastaurin Versus Lomustine in Glioblastoma | Biotech Hunter | Biotech Hunter