Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain

PHASE3CompletedINTERVENTIONAL
Enrollment

500

Participants

Timeline

Start Date

January 31, 1997

Study Completion Date

December 31, 2006

Conditions
Brain and Central Nervous System Tumors
Interventions
DRUG

carboplatin

DRUG

cisplatin

DRUG

etoposide phosphate

DRUG

ifosfamide

PROCEDURE

adjuvant therapy

PROCEDURE

conventional surgery

PROCEDURE

neoadjuvant therapy

RADIATION

radiation therapy

Trial Locations (21)

12

Our Lady's Hospital for Sick Children, Dublin

B4 6NH

Birmingham Children's Hospital, Birmingham

BS2 8AE

Institute of Child Health at University of Bristol, Bristol

CB2 2QQ

Addenbrooke's Hospital at Cambridge University Hospitals NHS Foundation Trust, Cambridge

LS9 7TF

Leeds Cancer Centre at St. James's University Hospital, Leeds

LE1 5WW

Leicester Royal Infirmary, Leicester

L12 2AP

Royal Liverpool Children's Hospital, Alder Hey, Liverpool

E1 1BB

Royal London Hospital, London

WC1N 3JH

Great Ormond Street Hospital for Children NHS Trust, London

M27 4HA

Central Manchester and Manchester Children's University Hospitals NHS Trust, Manchester

NE1 4LP

Sir James Spence Institute of Child Health, Newcastle upon Tyne

NG7 2UH

Queen's Medical Centre, Nottingham

0X3 9DU

Oxford Radcliffe Hospital, Oxford

S10 2TH

Children's Hospital - Sheffield, Sheffield

SO16 6YD

Southampton General Hospital, Southampton

SM2 5PT

Royal Marsden NHS Foundation Trust - Surrey, Sutton

BT12 6BE

Royal Belfast Hospital for Sick Children, Belfast

AB25 2ZG

Royal Aberdeen Children's Hospital, Aberdeen

EH9 1LF

Royal Hospital for Sick Children, Edinburgh

G3 8SJ

Royal Hospital for Sick Children, Glasgow

CF14 4XW

Childrens Hospital for Wales, Cardiff

All Listed Sponsors
lead

Children's Cancer and Leukaemia Group

OTHER

NCT00293358 - Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain | Biotech Hunter | Biotech Hunter