IVPCA in the Management of Pain Following Major Intracranial Surgery

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

159

Participants

Timeline

Start Date

March 31, 2006

Primary Completion Date

July 31, 2010

Study Completion Date

July 31, 2010

Conditions
Intracranial Surgery
Interventions
DRUG

PCA fentanyl

"PCA fentanyl 0.5 ug/kg with a dosing interval (lockout) of 15 minutes and a maximal permitted dosage of 4 demand doses per hour, according to their randomized preoperative assignment. The PCA pump (CADD-Solis Ambulatory Infusion Pump; Smiths Medical, Dublin, OH) had a preprogrammed dose limit of 50 ug fentanyl, and this was the maximal PCA dose permitted"

DRUG

PRN fentanyl

IV fentanyl 25 to 50 ug every 30 minutes PRN (the maximal routine dose permitted in our Neurosciences Critical Care Unit (NCCU))

Trial Locations (1)

21287

Johns Hopkins Hospital, Baltimore

All Listed Sponsors
lead

Johns Hopkins University

OTHER

NCT00286221 - IVPCA in the Management of Pain Following Major Intracranial Surgery | Biotech Hunter | Biotech Hunter