Use of Infliximab for the Treatment of Pemphigus Vulgaris

PHASE2CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

March 31, 2006

Primary Completion Date

December 31, 2010

Study Completion Date

March 31, 2011

Conditions
Pemphigus
Interventions
DRUG

Infliximab

Chimeric IgG monoclonal antibody that binds to TNF-alpha, generally used to treat Crohn's disease, given in a dosage of 5 mg/kg

OTHER

Placebo Comparator

Placebo administered in place of infliximab for control group

Trial Locations (4)

19104

University of Pennsylvania, Philadelphia

27710

Duke University Medical Center, Durham

52242

University of Iowa Hospitals and Clinics, Iowa City

90033

Norris Cancer Center, University of Southern California, Los Angeles

All Listed Sponsors
collaborator

Autoimmunity Centers of Excellence

OTHER

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT00283712 - Use of Infliximab for the Treatment of Pemphigus Vulgaris | Biotech Hunter | Biotech Hunter