Genistein and Interleukin-2 in Treating Patients With Metastatic Melanoma or Kidney Cancer

EARLY_PHASE1CompletedINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

November 30, 2005

Primary Completion Date

July 31, 2007

Study Completion Date

January 31, 2014

Conditions
Kidney CancerMelanoma (Skin)
Interventions
BIOLOGICAL

High-dose interleukin-2

Administered days 1-5, and 15-19; the patient will receive 600,000 IU/kg IL-2 by intravenous infusion over 15 minutes every 8 hours (on day 1 and day 15, patients will receive a maximum of 2 doses per day; on all other days in the cycle patients will receive a maximum of 3 doses per day)

DIETARY_SUPPLEMENT

genistein

Starting on day 10 and continuing through day 19, genistein will be administered orally at a dose of 600mg/day in two divided doses (i.e. 300mg po bid x 10 days)

Trial Locations (1)

60611-3013

Robert H. Lurie Comprehensive Cancer Center at Northwestern University, Chicago

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Northwestern University

OTHER

NCT00276835 - Genistein and Interleukin-2 in Treating Patients With Metastatic Melanoma or Kidney Cancer | Biotech Hunter | Biotech Hunter